| Type | Description |
|---|---|
| Definition | DNA meiotic recombinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:27:00 | Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures. | 33446654 |
| 2019-09-21 10:55:00 | To the best of our knowledge, this is the first report identifying DMC1 as the causative gene for human non-obstructive azoospermia and premature ovarian insufficiency. | 29331980 |
| 2019-05-11 13:03:00 | In this study, we created a mouse model of a putative infertility allele, DMC1M200V. DMC1 encodes a RecA homolog essential for meiotic recombination and fertility in mice..we found that Dmc1M200V/M200V male and female mice are fully fertile and do not exhibit any gonadal abnormalities | 30085085 |
| 2017-03-11 10:11:00 | Data indicate that ahomologous pairing by DMC1 protein or RAD51 recombinase in chromatin containing nucleosome-depleted double-stranded DNA (dsDNA) regions. | 27052786 |
| 2016-09-03 12:09:00 | BRCA2 protein stimulates DMC1-mediated DNA strand exchange between RPA-ssDNA complexes and duplex DNA, thus identifying BRCA2 as a mediator of DMC1 recombination function. | 26976601 |
| Type | IDs |
|---|---|
| Synonymous | DMC1H, LIM15, dJ199H16.1 |
| Gene |
UniProtKB-ID:
DMC1_HUMAN
UniprotKB:
Q14565
UniParc:
UPI00001294D1,
UPI0000421340
EMBL:
BC125164,
D63882,
BC125163,
CR456486,
AY520538,
AK297664,
AK292617,
AL022320,
D64108
Ensembl:
ENSG00000100206
KO:
hsa:11144
|
| Nucleutide sequences |
EMBL-CDS:
BAA10970.1,
AAI25165.1,
BAF85306.1,
AAR89915.1,
AAI25164.1,
CAG30372.1,
BAG60028.1,
BAA09932.1
Ensembl_TRS:
ENST00000216024,
ENST00000428462
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000412703,
ENSP00000216024
RefSeq:
XP_011528137.1,
NP_001265137.1,
XP_011528140.1,
NP_001349946.1,
XP_011528136.1,
XP_016884031.1,
XP_011528139.1,
NP_008999.2
|
| Others |
UniRef100:
UniRef100_Q14565
UniRef90:
UniRef90_Q14565
UniRef50:
UniRef50_Q14565
UniGene:
Hs.339396
CCDS:
CCDS63477.1,
CCDS13973.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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