TBC1D8 - TBC1 domain family member 8-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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11138 TBC1D8

基因描述

Type	Description
Definition	TBC1 domain family member 8

研究结论

Date	Results	Publications
2020-01-18 12:15:00	TBC1D8 drives ovarian cancer tumorigenesis and metabolic reprogramming and serves as an independent prognosis factor for ovarian cancer patients	30809301
2010-06-30 22:05:00	Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)	20548944
2010-01-21 00:00:00	isolated a TBC Rab-GAP cellular binding partner interacting with the N terminus of HCV NS5A; depleting the expression of this partner severely impairs HCV RNA replication with no obvious effect on cell viability	17686842

名称对应

Type	IDs
Synonymous	AD3, GRAMD8, HBLP1, TBC1D8A, VRP
Gene	UniProtKB-ID: TBCD8_HUMAN, J3KQ40_HUMAN UniprotKB: O95759, J3KQ40 UniParc: UPI000050A39A, UPI00015ADD19, UPI0001E8F205 EMBL: AB024057, AB449889, AK292826, AC016738, AC013722, AB017114 Ensembl: ENSG00000204634 KO: hsa:11138
Nucleutide sequences	EMBL-CDS: AAY14824.1, BAA76517.1, BAH16632.1, BAA75489.1, BAF85515.1 Ensembl_TRS: ENST00000376840, ENST00000409318
Protein sequencees	Ensembl_PRO: ENSP00000366036, ENSP00000386856 RefSeq: XP_016858687.1, XP_005263919.1, NP_001317277.1, XP_016858691.1, XP_005263921.1, NP_001095896.1, XP_011508809.1, XP_011508810.1, XP_016858688.1, XP_016858690.1, XP_016858689.1
Others	UniRef100: UniRef100_O95759, UniRef100_J3KQ40 UniRef90: UniRef90_O95759 UniRef50: UniRef50_O95759 UniGene: Hs.442657 CCDS: CCDS46375.1

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mRNA

Protein

UniprotKB

Description

Refseq

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全选

Pubmed编号	文献信息	发表日期	相关基因
32296183	A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G CotÃ© , Meaghan Daley , Steven Deimling , Alice Desbuleux , AmÃ©lie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , IstvÃ¡n A KovÃ¡cs , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood	2020-04-01	-
30809301	TBC1D8 Amplification Drives Tumorigenesis through Metabolism Reprogramming in Ovarian Cancer. Theranostics Min Chen , Xiu-Jie Sheng , Yuan-Yi Qin , Song Zhu , Qing-Xia Wu , Liqing Jia , Nan Meng , Yu-Tian He , Guang-Rong Yan	2019-01-01	-
26496610	A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell Marco Y Hein , Nina C Hubner , Ina Poser , JÃ¼rgen Cox , Nagarjuna Nagaraj , Yusuke Toyoda , Igor A Gak , Ina Weisswange , JÃ¶rg Mansfeld , Frank Buchholz , Anthony A Hyman , Matthias Mann	2015-10-22	Cep85l, Rcc1, Zbtb48, Bsdc1, Kifc1, Ccp110, Ints4, Slc6a8, Cenpi, Nup107, Xpo1, Fbxw11, Tubg1, Csnk1d, Bap1, Ptpn23, Tecpr2, Slain1, Ankrd28, Prkaa1, Espl1, Gbf1, Cdc20, Cenpf, Trip11, Mbd5, Kif22, Dut, Srsf1, Actb, Spred2, Akt2, Mta1, Tgs1, Pip4k2c, Ankfy1, Apc, Ar, Rhoa, Atp2a2, Atp5a1, Atp7a, Cep131, Bach1, Bcl7c, Bmpr1a, Brca1, Bub1, Bub1b, C1qbp, Anxa2, Calu, Cbx1, Cbx4, Cct2, Cct3, Cct4, Cct7, Cct8, Cd2ap, Cdk1, Cdc37, Cdh1, Chek1, Cit, Copa, Crebbp, Cry1, Csk, Smc3, Dctn1, Ddb1, Cdk2ap1, Mapre1, Ect2, Eef1a1, Eif3a, Mark2, Evpl, Ewsr1, Wdr5, Dclre1b, Fbl, Fgfr1, Flot1, Flot2, B4galt1, Gnb1, Gspt1, Hdac6, Herc2, Hsf1, Hsph1, Elavl1, Id2, Cyr61, Cep250, Insr, Eif3e
24104479	A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities. Mol. Syst. Biol. Franco J Vizeacoumar , Roland Arnold , Frederick S Vizeacoumar , Megha Chandrashekhar , Alla Buzina , Jordan T F Young , Julian H M Kwan , Azin Sayad , Patricia Mero , Steffen Lawo , Hiromasa Tanaka , Kevin R Brown , Anastasia Baryshnikova , Anthony B Mak , Yaroslav Fedyshyn , Yadong Wang , Glauber C Brito , Dahlia Kasimer , Taras Makhnevych , Troy Ketela , Alessandro Datti , Mohan Babu , Andrew Emili , Laurence Pelletier , Jeff Wrana , Zev Wainberg , Philip M Kim , Robert Rottapel , Catherine A O'Brien , Brenda Andrews , Charles Boone , Jason Moffat	2013-01-01	ADAM10, RAMP1, BCAS2, ANAPC10, CEBPD, CCT7, YME1L1, KDM5B, TBC1D8, TREX2, CREBBP, ZNF358, SREK1, C12orf66, CSNK2B, CDC42EP5, KIAA2026, COCH, DHFR, CYB5R3, RILPL2, EME2, ELK4, STK32A, ENO2, SLC36A1, FANCD2, VWCE, ALDH3B1, ATXN7L1, ICK, SNW1, SNRNP200, AKR1B1, RFTN1, SLC9A8, PIGN, KPNA6, OSBP2, MMS22L, PRPF31, FBXL6, BLOC1S1, PLEK2, POLM, GPER1, C16orf72, GTPBP8, SLC25A6, ZBTB48, XIAP, ST8SIA6, ZNF181, IDH2, KRAS, HES5, LLGL2, LTA4H, LTK, MXD1, MBP, MDFI, DNAJB9, MTNR1A, NAB1, NONO, NOTCH1, NUMA1, NUP98, OPRL1, PBX3, TXNDC11, NDUFA13, TFB1M, RNFT1, POLR3K, LUC7L3, FXYD1, POLD2, POLR2L, POU3F3, INO80, SAMD4B, HES6, TTC27, CDC37L1, CDK5RAP2, KMT2E, NXT2, MAP2K1, B2M, PSMA3, PSMB2, DUS3L, ARNTL2, NT5M, PSMD1, PTEN, CWC22
22779921	A yeast two-hybrid screen reveals that osteopontin associates with MAP1A and MAP1B in addition to other proteins linked to microtubule stability, apoptosis and protein degradation in the human brain. Eur. J. Neurosci. Philip Long , Parwez Samnakay , Peter Jenner , Sarah Rose	2012-09-01	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
20548944	An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits. PLoS Genet Yi-Hsiang Hsu , M Carola Zillikens , Scott G Wilson , Charles R Farber , Serkalem Demissie , Nicole Soranzo , Estelle N Bianchi , Elin Grundberg , Liming Liang , J Brent Richards , Karol Estrada , Yanhua Zhou , Atila van Nas , Miriam F Moffatt , Guangju Zhai , Albert Hofman , Joyce B van Meurs , Huibert A P Pols , Roger I Price , Olle Nilsson , Tomi Pastinen , L Adrienne Cupples , Aldons J Lusis , Eric E Schadt , Serge Ferrari , AndrÃ© G Uitterlinden , Fernando Rivadeneira , Timothy D Spector , David Karasik , Douglas P Kiel	2010-06-10	-
19077034	Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity. Genes Cells Koutaro Ishibashi , Eiko Kanno , Takashi Itoh , Mitsunori Fukuda	2009-01-01	Rab3a, Rab3a, Tbc1d10b, TBC1D7-LOC100130357, TBC1D8, EVI5L, TBC1D16, TBC1D20, SGSM1, TBC1D21, RAB3GAP1, TBC1D9B, TBC1D9, TBC1D1, TBC1D12, TBC1D30, RABGAP1, TBC1D22A, TBC1D10B, SGSM3, TBC1D26, TBC1D25, TBC1D7, TBC1D13, TBC1D8B, TBC1D19, TBC1D2, TBC1D22B, TBC1D23, TBC1D24, TBC1D14, TBC1D15, TBC1D3, EVI5, TBC1D17, GRTP1, TBC1D10A, TBC1D3F, USP6, TBCK, USP6NL, TBC1D5, TBC1D4, SGSM2, RABGAP1L
17686842	A Rab-GAP TBC domain protein binds hepatitis C virus NS5A and mediates viral replication. J. Virol. Ella H Sklan , Kirk Staschke , Tina M Oakes , Menashe Elazar , Mark Winters , Benjamin Aroeti , Tsafi Danieli , Jeffrey S Glenn	2007-10-01	HCVgp1, TBC1D8, TBC1D20
17646400	Functional dissection of Rab GTPases involved in primary cilium formation. J. Cell Biol. Shin-Ichiro Yoshimura , Johannes Egerer , Evelyn Fuchs , Alexander K Haas , Francis A Barr	2007-07-30	OPTN, TBC1D7-LOC100130357, TBC1D8, EVI5L, TBC1D16, TBC1D20, TBC1D21, ARL13B, TBC1D9B, TBC1D2B, TBC1D1, TBC1D30, RABGAP1, TBC1D22A, TBC1D10B, SGSM3, TBC1D10C, RAB15, ARL2, ARL3, RAB8A, ODF2, TBC1D7, RAB14, RAB23, RAB8B, TBC1D13, TBC1D19, TBC1D2, TBC1D22B, TBC1D24, TBC1D14, RAB1A, RAB17, TBC1D15, TBC1D3, EVI5, TBC1D17, TBC1D10A, ARL6, IFT20, USP6NL, TBC1D5

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