| Type | Description |
|---|---|
| Definition | kinesin family member 3A |
| Date | Results | Publications |
|---|---|---|
| 2020-09-12 16:03:00 | Disease-associated KIF3A variants alter gene methylation and expression impacting skin barrier and atopic dermatitis risk. | 32796837 |
| 2020-04-25 10:16:00 | Silencing of KIF3A suppressed TNBC cell proliferation by repressing the Rb-E2F signaling pathway and inhibited migration and invasion by repressing epithelial-mesenchymal transition. The tumor size was smaller and the number of lung metastatic nodules was lower in KIF3A depletion MDA-MB-231 cell xenograft mice than in the negative control group. In addition, KIF3A overexpression correlated with chemoresistance. | 32011034 |
| 2020-01-04 11:31:00 | Study demonstrates that human ICK (intestinal cell kinase) that authors herein call CAPK (ciliopathy-associated protein kinase) interacts with human KIF3A and phosphorylates a conserved site Thr672 both in vitro and in vivo. Long, unstructured, non-catalytic carboxyl-terminal domain (CTD) of CAPK is required for this interaction with and phosphorylation of KIF3A | 31277411 |
| 2019-05-25 11:10:00 | the association of KIF3A is with asthma + eczema. The presence of AR comorbidity did not increase the genetic association of KIF3A with asthma or even with asthma + eczema. Thus, asthma + eczema constitutes a distinct asthmatic phenotype characterized by an association with KIF3A SNPs, which is not strengthened by AR. | 28238750 |
| 2018-08-11 11:48:00 | KIF3A plays an important role in epithelium apoptosis and bronchial inflammation in asthma | 29156524 |
| Type | IDs |
|---|---|
| Synonymous | FLA10, KLP-20 |
| Gene |
UniProtKB-ID:
KIF3A_HUMAN,
Q05CT3_HUMAN,
B4DHG8_HUMAN,
J3KPF9_HUMAN,
E9PES4_HUMAN
UniprotKB:
Q9Y496,
Q05CT3,
B4DHG8,
J3KPF9,
E9PES4
UniParc:
UPI00017A6ED1,
UPI0001610E8D,
UPI0000E573A8,
UPI000035B258,
UPI000066DA09
EMBL:
AK295089,
AB209780,
AC004039,
AF041853,
AC004237,
BC045542,
BC020890
Ensembl:
ENSG00000131437
KO:
hsa:11127
|
| Nucleutide sequences |
EMBL-CDS:
AAC72294.1,
AAC04475.1,
AAH45542.1,
BAD93017.1,
AAH20890.1,
BAG58130.1
Ensembl_TRS:
ENST00000378746,
ENST00000378735,
ENST00000403231
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000368020,
ENSP00000368009,
ENSP00000385808
RefSeq:
XP_016864484.1,
XP_006714589.1,
NP_001287720.1,
NP_001287721.1,
XP_016864485.1,
NP_008985.3
|
| Others |
UniRef100:
UniRef100_E9PES4,
UniRef100_Q9Y496,
UniRef100_Q05CT3,
UniRef100_B4DHG8,
UniRef100_J3KPF9
UniRef90:
UniRef90_E9PES4,
UniRef90_Q9Y496,
UniRef90_Q5R4H3,
UniRef90_Q8CGJ1
UniRef50:
UniRef50_Q8CGJ1,
UniRef50_Q9Y496,
UniRef50_P28741
UniGene:
Hs.43670
CCDS:
CCDS34235.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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