| Type | Description |
|---|---|
| Definition | Fas associated factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:30:00 | Germline Mutations in FAF1 Are Associated With Hereditary Colorectal Cancer. | 32179092 |
| 2019-11-30 11:43:00 | the mechanisms of FAF1/SIM-mediated MR transrepression involve inhibition of MR N/C interactions and promotion of MR polyubiquitination and degradation. | 30935967 |
| 2019-07-20 12:06:00 | C18H17NO6 and Scutellarin in the study. In molecular level, the mRNA and protein expression of Fas-associated factor 1 (FAF1) expression in U251 and LN229 were upregulated by C18H17NO6 and its combination with Scutellarin, especially the protein expression. | 30915356 |
| 2019-07-13 12:26:00 | These findings establish FAF1 as a modulator of MAVS and uncover mechanisms that regulate FAF1 to insure timely activation of antiviral defense. | 30472208 |
| 2018-12-01 12:30:00 | Data show that activated proto-oncogene protein Akt (AKT) directly phosphorylates Fas associated factor 1 (FAF1) reduces FAF1 at the plasma membrane and results in an increase in TGF-beta type II receptor (TbetaRII) at the cell surface. | 28443643 |
| Type | IDs |
|---|---|
| Synonymous | CGI-03, HFAF1s, UBXD12, UBXN3A, hFAF1 |
| Gene |
UniProtKB-ID:
FAF1_HUMAN
UniprotKB:
Q9UNN5
UniParc:
UPI000002A953,
UPI0000032C67
EMBL:
CH471059,
AC118557,
AF106798,
AC091610,
BC004970,
AF094700,
AL359977,
AF132938,
AL603746,
AL049637,
BC067100,
AL133631,
AJ271408,
AF136173
Ensembl:
ENSG00000185104
KO:
hsa:11124
|
| Nucleutide sequences |
EMBL-CDS:
AAP97263.1,
EAX06837.1,
AAH67100.1,
CAB63755.1,
AAD51876.1,
AAD27713.1,
AAH04970.1,
AAD51886.1,
CAB67705.1
Gene_ORFName:
CGI-03
Ensembl_TRS:
ENST00000396153
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000379457
RefSeq:
XP_016855625.1,
XP_024308502.1,
NP_008982.1,
XP_024308504.1
|
| Others |
UniRef100:
UniRef100_Q9UNN5
UniRef90:
UniRef90_Q9UNN5
UniRef50:
UniRef50_Q9UNN5
UniGene:
Hs.530402
CCDS:
CCDS554.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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