| Type | Description |
|---|---|
| Definition | protein tyrosine phosphatase receptor type T |
| Date | Results | Publications |
|---|---|---|
| 2020-04-04 10:07:00 | Study revealed a significantly higher prevalence of PTPRT and JAK2 mutations in lung adenocarcinomas among African Americans compared with European Americans. Patients carrying these mutations have a concomitant increase in signaling and miR-21 expression. | 31844068 |
| 2019-07-13 11:37:00 | A novel de novo 20q13.11q13.12 microdeletion was found in a boy with neurodevelopmental disorders. The established function of the PTPRT gene suggests that haploinsuficiency of this gene may result in the clinical features observed in our patient: stereotype movements, nervous tics, social and emotional disturbances and attention-span deficits. | 28796977 |
| 2017-07-22 11:21:00 | The single cell genotyping not only confirmed the co-occurrence of the PTPRT, CAND1 and DOCK6 mutations in the same AML clone but also revealed a clonal hierarchy, as the PTPRT mutation was likely acquired after the CAND1 and DOCK6 mutations. | 27244256 |
| 2016-08-06 10:22:00 | PTPRT promoter methylation is significantly associated with sensitivity to inhibition in HNSCC cells, suggesting that PTPRT promoter methylation may serve as a predictive biomarker for responsiveness to duanyu18133 inhibitors in clinical development | 25982282 |
| 2016-02-13 11:38:00 | Data reported evidence that rs2866943 polymorphism in PTPRT 3'-UTR was involved in the occurrence of esophageal squamous cell carcinoma by acting as a protective factor while rs6029959 acts as a risk factor. | 25967969 |
| Type | IDs |
|---|---|
| Synonymous | RPTPrho |
| Gene |
UniProtKB-ID:
PTPRT_HUMAN,
A0A075B6H0_HUMAN
UniprotKB:
O14522,
A0A075B6H0
UniParc:
UPI00001AF6FA,
UPI0000246C03,
UPI000020653F
EMBL:
AL031656,
AL049812,
AB006621,
AL035459,
AL031676,
Z93942,
AL117374,
AL136461,
AF043644,
AL035666,
AL109826,
AL024473,
AL121763,
BC153300,
AL021395,
AL022239,
AL359695,
KF456910,
KF456906
Ensembl:
ENSG00000196090
KO:
hsa:11122
|
| Nucleutide sequences |
EMBL-CDS:
AAI53301.1,
BAA22952.2,
AAD09421.2
Ensembl_TRS:
ENST00000373187,
ENST00000373193,
ENST00000373198
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000362289,
ENSP00000362283,
ENSP00000362294
RefSeq:
NP_008981.4,
XP_016883101.1,
XP_024307588.1,
XP_016883102.1,
NP_573400.3,
XP_016883100.1
|
| Others |
UniRef100:
UniRef100_O14522,
UniRef100_A0A075B6H0
UniRef90:
UniRef90_O14522
UniRef50:
UniRef50_O14522
UniGene:
Hs.526879
CCDS:
CCDS42874.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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