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1112 FOXN3

1112

FOXN3

forkhead box N3

protein-coding

Homo sapiens

基因描述

Type Description
Definition forkhead box N3

研究结论

Date Results Publications
2021-04-03 13:30:00 MicroRNA-574-5p directly targets FOXN3 to mediate thyroid cancer progression via Wnt/beta-catenin signaling pathway. 32284251
2021-01-02 12:49:00 The clinical and prognostic significance of FOXN3 downregulation in acute myeloid leukaemia. 32078244
2020-09-12 15:32:00 FOXN3 was notably downregulated in osteosarcoma (OS) tissues and the expression of FOXN3 was negatively correlated with tumor size, metastasis and TNM stage. Also, FOXN3 suppressed the proliferation, migration and invasion of osteosarcoma cells. Furthermore, FOXN3 was demonstrated to transcriptionally suppress SIRT6 expression, thereby inhibiting MMP9 secretion. 30483801
2019-11-09 12:46:00 liver FOXN3 and glucagon control fasting glucose. 29996093
2019-11-09 12:41:00 these results identified a negative cross-regulatory loop between ERalpha and CHES1 that was required for growth of breast cancer cells, it might uncover novel insight into molecular mechanism of CHES1 involved in breast cancer and provide new avenues for molecular-targeted therapy in hormone-regulated breast cancer. 29752474

名称对应

Type IDs
Synonymous C14orf116, CHES1, PRO1635
Gene
UniProtKB-ID: FOXN3_HUMAN, A0A024R6I1_HUMAN
UniprotKB: O00409, A0A024R6I1
UniParc: UPI000003B451, UPI000002AA09
EMBL: AL356805, CH471061, AC007263, U68723, BC007506, AL138478, AL357093
Ensembl: ENSG00000053254
KO: hsa:1112
Nucleutide sequences
EMBL-CDS: AAF18259.1, AAH07506.1, AAB58252.1, EAW81403.1, EAW81404.1, EAW81406.1, EAW81405.1
Gene_ORFName: hCG_2028955
Ensembl_TRS: ENST00000345097, ENST00000615335, ENST00000557258, ENST00000261302, ENST00000555353
Protein sequencees
Ensembl_PRO: ENSP00000261302, ENSP00000479114, ENSP00000343288, ENSP00000452005, ENSP00000452227
RefSeq: NP_005188.2, NP_001078940.1
Others
UniRef100: UniRef100_O00409
UniRef90: UniRef90_O00409
UniRef50: UniRef50_O00409
UniGene: Hs.434286
CCDS: CCDS41977.1, CCDS32138.1

全选

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研究热度

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