| Type | Description |
|---|---|
| Definition | citron rho-interacting serine/threonine kinase |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:31:00 | Down-regulation of CIT can inhibit the growth of human bladder cancer cells. | 31972359 |
| 2020-07-25 12:12:00 | gene expression profile data set showed that MM patients with high CIT gene expression had significantly worse overall survival compared with MM patients with low CIT gene expression. CIT silencing in MM cell lines induced cytokinesis failure and resulted in decreased MM cell proliferation in vitro and in vivo. | 30940634 |
| 2019-12-07 12:26:00 | CIT-K overexpression is associated with breast cancer. | 30565087 |
| 2019-09-28 12:40:00 | CITK deletion decreased tumor growth and increased overall survival in these mice, with no apparent side effects. These results suggest that CITK can be a useful molecular target for medulloblastoma treatment. | 29921697 |
| 2017-07-29 12:54:00 | in this study we have provided evidence that ASPM controls spindle orientation by regulating the dynamics of astral MT and that CITK is a critical downstream partner of ASPM for this activity. | 27562601 |
| Type | IDs |
|---|---|
| Synonymous | CITK, CRIK, MCPH17, STK21 |
| Gene |
UniProtKB-ID:
CTRO_HUMAN
UniprotKB:
O14578
UniParc:
UPI0000683C41,
UPI000053E928,
UPI00001908FD,
UPI000049E307
EMBL:
AC002563,
AY209000,
AY681966,
AY257469,
AC004813,
AB023166,
AC079317
Ensembl:
ENSG00000122966
KO:
hsa:11113
|
| Nucleutide sequences |
EMBL-CDS:
AAV87216.1,
AAP43922.1,
BAA76793.2,
AAP13528.1,
AAB71327.1
Ensembl_TRS:
ENST00000612548,
ENST00000261833,
ENST00000392521
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000482318,
ENSP00000376306,
ENSP00000261833
RefSeq:
XP_016874224.1,
XP_011536094.1,
XP_011536091.1,
NP_001193928.1,
XP_011536089.1,
XP_016874225.1,
NP_009105.1,
XP_016874226.1,
XP_011536092.1,
XP_006719269.1,
XP_011536086.1,
XP_011536087.1,
XP_011536085.1,
XP_011536093.1,
XP_016874228.1,
XP_011536090.1,
XP_016874227.1
|
| Others |
UniRef100:
UniRef100_O14578
UniRef90:
UniRef90_O14578
UniRef50:
UniRef50_O14578
UniGene:
Hs.119594
CCDS:
CCDS55891.1,
CCDS9192.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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