| Type | Description |
|---|---|
| Definition | PR/SET domain 7 |
| Date | Results | Publications |
|---|---|---|
| 2016-12-17 10:10:00 | These studies indicate that after a single serine to tyrosine mutation at residue 357 (S357Y), PRDM7 regains the substrate specificities and catalytic activities similar to its evolutionary predecessor, including the ability to efficiently methylate H3K36. | 27129774 |
| 2008-05-30 15:37:00 | Evolutionary analysis suggests that human PRDM7 and PRDM9 genes, a pair of close paralogs corresponding to a single mouse gene Prdm9, were generated by a recent gene duplication event after the divergence of the ancestors of human and mouse. | 18231586 |
| Type | IDs |
|---|---|
| Synonymous | PFM4, ZNF910 |
| Gene |
UniProtKB-ID:
PRDM7_HUMAN
UniprotKB:
Q9NQW5
UniParc:
UPI000002B18B,
UPI00018E1827,
UPI00015294E9
EMBL:
AM690991,
AF274348,
CH471184,
BC107033,
AF274347
Ensembl:
ENSG00000126856
KO:
hsa:11105
|
| Nucleutide sequences |
EMBL-CDS:
AAI07034.1,
CAM84449.1,
AAF78084.1,
EAW66654.1,
AAF78085.1
Ensembl_TRS:
ENST00000449207,
ENST00000643008
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000396732,
ENSP00000496449
RefSeq:
XP_011521133.1,
XP_016878373.1,
XP_016878372.1,
NP_001091643.1,
XP_016878371.1,
XP_011521131.1
|
| Others |
UniRef100:
UniRef100_Q9NQW5
UniRef90:
UniRef90_Q9NQW5
UniRef50:
UniRef50_Q9NQW5
UniGene:
Hs.406695
CCDS:
CCDS45557.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30948266 |
Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation. Mol Cell Shih-Han Lee , Christine Mayr |
2019-05-16 | - |
| 30021884 |
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei. Mol Cell Proteomics Domenico Fasci , Hugo van Ingen , Richard A Scheltema , Albert J R Heck |
2018-10-01 | - |
| 27129774 |
PR Domain-containing Protein 7 (PRDM7) Is a Histone 3 Lysine 4 Trimethyltransferase. J Biol Chem Levi L Blazer , Evelyne Lima-Fernandes , Elisa Gibson , Mohammad S Eram , Peter Loppnau , Cheryl H Arrowsmith , Matthieu Schapira , Masoud Vedadi |
2016-06-24 | - |
| 25416956 |
A proteome-scale map of the human interactome network. Cell Thomas Rolland , Murat TaÅan , Benoit Charloteaux , Samuel J Pevzner , Quan Zhong , Nidhi Sahni , Song Yi , Irma Lemmens , Celia Fontanillo , Roberto Mosca , Atanas Kamburov , Susan D Ghiassian , Xinping Yang , Lila Ghamsari , Dawit Balcha , Bridget E Begg , Pascal Braun , Marc Brehme , Martin P Broly , Anne-Ruxandra Carvunis , Dan Convery-Zupan , Roser Corominas , Jasmin Coulombe-Huntington , Elizabeth Dann , Matija Dreze , Amélie Dricot , Changyu Fan , Eric Franzosa , Fana Gebreab , Bryan J Gutierrez , Madeleine F Hardy , Mike Jin , Shuli Kang , Ruth Kiros , Guan Ning Lin , Katja Luck , Andrew MacWilliams , Jörg Menche , Ryan R Murray , Alexandre Palagi , Matthew M Poulin , Xavier Rambout , John Rasla , Patrick Reichert , Viviana Romero , Elien Ruyssinck , Julie M Sahalie , Annemarie Scholz , Akash A Shah , Amitabh Sharma , Yun Shen , Kerstin Spirohn , Stanley Tam , Alexander O Tejeda , Shelly A Trigg , Jean-Claude Twizere , Kerwin Vega , Jennifer Walsh , Michael E Cusick , Yu Xia , Albert-László Barabási , Lilia M Iakoucheva , Patrick Aloy , Javier De Las Rivas , Jan Tavernier , Michael A Calderwood , David E Hill , Tong Hao , Frederick P Roth , Marc Vidal |
2014-11-20 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 19274049 |
A census of human transcription factors: function, expression and evolution. Nat Rev Genet Juan M Vaquerizas , Sarah K Kummerfeld , Sarah A Teichmann , Nicholas M Luscombe |
2009-04-01 | - |
| 18187620 |
Identification of host proteins required for HIV infection through a functional genomic screen. Science Abraham L Brass , Derek M Dykxhoorn , Yair Benita , Nan Yan , Alan Engelman , Ramnik J Xavier , Judy Lieberman , Stephen J Elledge |
2008-02-15 |
gag,
gag-pol,
vif,
vpr,
tat,
rev,
vpu,
env,
nef,
MED6,
PIGK,
HUWE1,
PDIA6,
MPHOSPH6,
ADAM10,
RABEPK,
RRAGB,
ATG7,
ARPC1A,
POLR3F,
LEFTY1,
PNRC1,
TMED2,
PRDM7,
POLR3A,
ERI2,
SLC46A1,
SFT2D1,
GABARAPL2,
CARD16,
PKD1L2,
XKR4,
AGAP2,
AP2M1,
CLN3,
CLNS1A,
ERP27,
ANKRD9,
ZNF720,
RPTN,
ARHGEF19,
ZNF831,
C4orf33,
SOWAHA,
C9orf131,
RIMS4,
FAM76B,
ZNF785,
LYPD4,
PM20D1,
IQUB,
ZNF791,
DDOST,
DDX3X,
DMXL1,
DDX10,
TIMM8A,
DDX53,
EDNRA,
AGO3,
EGF,
EGFR,
CRTC2,
EPS8,
ERCC3,
AKT1,
AKT2,
ETF1,
DOK6,
C6orf1,
LNX2,
FHL3,
COG2,
TRAPPC8,
ANKRD6,
BAHD1,
FBXO21,
WDTC1,
FLII,
SEPT8,
MDN1,
OTUD3,
SCFD1,
NUP160,
FBXW11,
ARHGEF12,
FNTA,
PIP5K1C,
PHF3,
ETHE1,
TNPO3,
KLHDC2,
MKRN2,
COG4,
TRIM58,
INTS7,
SPATS2L,
GAPVD1,
RSL1D1
|
| 18231586 |
Genome-wide survey and developmental expression mapping of zebrafish SET domain-containing genes. PLoS ONE Xiao-Jian Sun , Peng-Fei Xu , Ting Zhou , Ming Hu , Chun-Tang Fu , Yong Zhang , Yi Jin , Yi Chen , Sai-Juan Chen , Qiu-Hua Huang , Ting Xi Liu , Zhu Chen |
2008-01-01 |
prdm4,
whsc1,
setd8b,
ehmt1a,
arrdc1a,
whsc1l1,
prdm1c,
kmt2d,
setd8c,
prdm12a,
prdm6,
smyd1a,
setd6,
prdm1a,
kmt2e,
suv39h1b,
setdb2,
rmnd5b,
prdm9,
ehmt1b,
prdm8,
prdm5,
setd7,
suv39h1a,
smyd5,
mecom,
smyd2a,
setdb1a,
nsd1a,
setd1a,
kmt2a,
prdm8b,
galnt11,
prdm16,
kmt2ca,
kmt2ba,
prdm14,
ash1l,
setmar,
nsd1b,
prdm11,
fam134c,
ramp2,
prdm15,
kmt2bb,
setd1ba,
kmt2cb,
prkag2b,
smyd2b,
smyd1b,
suv420h2,
ehmt2,
smyd3,
prdm1b,
setd5,
foxp3a,
setd1bb,
suv420h1,
rhof,
ezh1,
setd8a,
smyd4,
setdb1b,
ezh2,
setd2,
prdm13,
prdm2b,
PRDM7,
KMT2E,
PRDM9,
SUV39H2
|
| 17916234 |
BMC Evol Biol Irene Fumasoni , Natalia Meani , Davide Rambaldi , Gaia Scafetta , Myriam Alcalay , Francesca D Ciccarelli |
2007-10-04 | - |
| 14759258 |
An unappreciated role for RNA surveillance. Genome Biol. R Tyler Hillman , Richard E Green , Steven E Brenner |
2004-01-01 |
DPP3,
TSPAN32,
USH1C,
ADARB1,
RBCK1,
CELF1,
B3GNT2,
FTCD,
TUBGCP2,
RBPMS,
TRIM31,
PRDM7,
CAPN10,
LYST,
CLK1,
CLK2,
CLK3,
CLN3,
CMKLR1,
ABCC13,
DFFB,
DMPK,
DTNB,
EPHA3,
ESR2,
FCAR,
SNX13,
FOLR3,
GABBR1,
COG4,
ERAL1,
DAOA,
GFRA1,
GLS,
DONSON,
HFE,
DNAJB2,
FAS,
IRF7,
KCNQ2,
KLK2,
MAN2A2,
MAP2,
MAP4,
MAX,
ADAM11,
MSR1,
ATF3,
ATP1A1,
NPR2,
KCNK4,
C6orf48,
MLXIPL,
LEF1,
CRNKL1,
PDE4A,
PLAT,
ADAM22,
CSNK1G1,
SETD4,
PPEF1,
IL17RB,
KLK15,
C20orf24,
NXF5,
CPXM1,
PSEN1,
PSMA7,
MAP3K7CL,
PSMD4,
PTPRD,
RAD51D,
SRSF5,
SH3BP2,
SHOX2,
CYP3A43,
BMP1,
SNTB2,
SON,
MED22,
ZAN,
CALCA,
AKAP1,
AKAP17A,
COLQ,
BCL2L12,
HDAC10,
CASP8,
ANTXR1,
CASP10,
CHRD,
ABCC3,
TNFRSF25,
TNFRSF10B,
CFLAR,
IL1RL1,
ITGB1BP1,
ZFYVE9,
PPT2
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员