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11104 KATNA1

11104

KATNA1

katanin catalytic subunit A1

protein-coding

Homo sapiens

基因描述

Type Description
Definition katanin catalytic subunit A1

研究结论

Date Results Publications
2020-03-14 12:56:00 structures of the apo and ATPgammaS-bound states of the catalytic AAA domain of human katanin p60 at 3.0 and 2.9 A resolution, respectively, are reported. 30699360
2019-12-07 10:31:00 In this study, we identified the main regulatory region of KATNA1 gene encoding katanin-p60 as which has a key role for its expression, and showed Elk1 binding to KATNA1. Furthermore, we identified that Elk1 decreased katanin-p60 and spastin protein expressions, while mRNA levels were increased upon Elk1 overexpression. 30789974
2019-10-19 12:11:00 targeting an active version of katanin p60 to the kinetochore can reduce the fidelity of achieving full chromosome alignment in metaphase and could serve as a microtubule disruption tool for the future. 30176123
2018-02-24 10:17:00 CAMSAP3 precisely coordinates with dynein and katanin to regulate the microtubule detachment process. 28386021
2017-09-09 11:49:00 ASPM-katanin complex controls microtubule disassembly at spindle poles and that misregulation of this process can lead to microcephaly. 28436967

名称对应

Type IDs
Gene
UniProtKB-ID: KTNA1_HUMAN, A8K7S5_HUMAN
UniprotKB: O75449, A8K7S5
UniParc: UPI00015DA9C6, UPI0000071D68, UPI000018CE8A
EMBL: AK292090, CH471051, AL078581, BC050428, BX276089, AF056022
Ensembl: ENSG00000186625
KO: hsa:11104
Nucleutide sequences
EMBL-CDS: EAW47795.1, AAH50428.1, EAW47793.1, AAC25114.1, BAF84779.1
Ensembl_TRS: ENST00000335643, ENST00000335647, ENST00000367411
Protein sequencees
Ensembl_PRO: ENSP00000335180, ENSP00000335106, ENSP00000356381
RefSeq: XP_005266861.1, XP_016865696.1, NP_008975.1, XP_024302085.1, XP_016865697.1, XP_016865699.1, NP_001191005.1, XP_016865698.1, XP_005266862.1
Others
UniRef100: UniRef100_A8K7S5, UniRef100_O75449
UniRef90: UniRef90_O75449
UniRef50: UniRef50_O75449
UniGene: Hs.450175
CCDS: CCDS56456.1, CCDS5217.1

全选

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