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110935 Atp6v1b1

110935

Atp6v1b1

ATPase, H+ transporting, lysosomal V1 subunit B1

protein-coding

Mus musculus

基因描述

Type Description
Definition ATPase, H+ transporting, lysosomal V1 subunit B1

研究结论

Date Results Publications
2020-03-07 10:13:00 involvement of ICs in water homeostasis, at least partly mediated by V-ATPase, in a sex-dependent manner 31386675
2019-07-13 10:10:00 ATP6V1B1 is expressed in the early distal nephron. The physiological importance of H(+)-ATPase expression in these segments remains to be delineated. 29993276
2018-12-22 12:31:00 RhCG and H+ATPases are located within the same cellular protein complex in the kidney and this interaction is required for maximal urinary acidification by H+-ATPases, a prerequisite for efficient NH3 secretion and urine excretion of NH4+. 29054531
2018-08-18 10:37:00 1) Atp6v1b1+/- mice developed a mild incomplete dRTA. dRTA is partly compensated by respiration. 2) Compensatory mechanisms for the absence of B1 take place only in the collecting duct of Atp6v1b1-/- kidneys. 29843146
2018-01-27 11:46:00 Because MRL-Atp6v1b1vxt/vtx mice do not recapitulate the metabolic acidosis of dRTA patients, they provide a new genetic model for nonsyndromic deafness with enlarged vestibular aqueduct (EVA; OMIM #600791). 28934385

名称对应

Type IDs
Synonymous AW208839, Atp6b1, D630003L15, D630030L16Rik, D630039P21Rik, Vpp-3, Vpp3
Gene
UniProtKB-ID: Q91YH6_MOUSE
UniprotKB: Q91YH6
UniParc: UPI00000296AE
EMBL: BC017127, AK168980, AK052604, AF435091, AK078810, AC090647, AK052707
Ensembl: ENSMUSG00000006269
KO: mmu:110935
Nucleutide sequences
EMBL-CDS: BAC35059.1, AAH17127.1, BAC35108.1, BAE40781.1, BAC37404.1, AAN45856.1
Ensembl_TRS: ENSMUST00000006431
Protein sequencees
Ensembl_PRO: ENSMUSP00000006431
RefSeq: NP_598918.1
Others
UniRef100: UniRef100_Q91YH6
UniRef90: UniRef90_Q91YH6
UniRef50: UniRef50_P15313
UniGene: Mm.220823

全选

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