| Type | Description |
|---|---|
| Definition | solute carrier family 8 (sodium/calcium exchanger), member 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:20:00 | TGF-beta Signaling Regulates SLC8A3 Expression and Prevents in Developing Midbrain Dopaminergic and Dorsal Raphe Serotonergic Neurons. | 32326436 |
| 2019-11-09 10:14:00 | NCX1 was exclusively co-expressed in IBA-1-positive microglial cells in the striatum, whereas NCX3 was solely co-expressed in tyrosine hydroxylase-positive neurons in substantia nigra. | 29941946 |
| 2019-09-21 11:07:00 | preconditioning prevented NCX3 downregulation in SOD1 G93A mice spinal cord, leading to an increased number of motor neurons associated to a reduced astrogliosis, and reduced the denervation of neuromuscular junctions observed in SOD1 G93A mice. | 29434186 |
| 2018-11-24 12:22:00 | NCX2 and NCX3 protein and mRNA levels are relatively reduced in hippocampal CA1 of APP23 and APP-KI mice. Likewise, NCX2(+/-) or NCX3(+/-) mice exhibited impaired hippocampal LTP and memory-related behaviors. Moreover, relative to controls, calcium/calmodulin-dependent protein kinase II (CaMKII) autophosphorylation significantly decreased in NCX2(+/-) mouse hippocampus but increased in hippocampus of NCX3(+/-) mice. | 29274751 |
| 2018-01-06 10:47:00 | This study demonstrate that knocking-out NCX3 impairs oligodendrocyte response and worsens clinical symptoms in EAE without altering the immune T-cell population. | 27120265 |
| Type | IDs |
|---|---|
| Synonymous | AW742262, Ncx3 |
| Gene |
UniProtKB-ID:
NAC3_MOUSE,
Q3UTP5_MOUSE,
E9PX50_MOUSE,
Q8BXN1_MOUSE
UniprotKB:
S4R2P9,
Q3UTP5,
E9PX50,
Q8BXN1
UniParc:
UPI0000F4A3C3,
UPI00005ABECA,
UPI000019B058,
UPI00000EA655,
UPI00033353FA
EMBL:
AK165197,
AC124384,
BC080862,
BC052435,
AK044636,
AF453257,
AK139260
Ensembl:
ENSMUSG00000079055
KO:
mmu:110893
|
| Nucleutide sequences |
EMBL-CDS:
AAL39160.1,
AAH80862.1,
AAH52435.1,
BAE38073.1,
BAE23935.1,
BAC32013.1
Ensembl_TRS:
ENSMUST00000085238,
ENSMUST00000182208,
ENSMUST00000064594
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000138735,
ENSMUSP00000082334,
ENSMUSP00000063258
RefSeq:
XP_036013060.1,
NP_536688.2,
XP_006515477.1,
XP_036013059.1,
XP_006515474.1,
NP_001161392.1,
XP_030102387.1,
XP_036013058.1
|
| Others |
UniRef100:
UniRef100_S4R2P9,
UniRef100_Q3UTP5,
UniRef100_Q8BXN1,
UniRef100_E9PX50
UniRef90:
UniRef90_S4R2P9,
UniRef90_Q8BXN1
UniRef50:
UniRef50_A0A250Y381,
UniRef50_S4R2P9
UniGene:
Mm.443748
CCDS:
CCDS49103.1,
CCDS36485.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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