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110891 Slc8a2

110891

Slc8a2

solute carrier family 8 (sodium/calcium exchanger), member 2

protein-coding

Mus musculus

基因描述

Type Description
Definition solute carrier family 8 (sodium/calcium exchanger), member 2

研究结论

Date Results Publications
2018-11-24 12:22:00 NCX2 and NCX3 protein and mRNA levels are relatively reduced in hippocampal CA1 of APP23 and APP-KI mice. Likewise, NCX2(+/-) or NCX3(+/-) mice exhibited impaired hippocampal LTP and memory-related behaviors. Moreover, relative to controls, calcium/calmodulin-dependent protein kinase II (CaMKII) autophosphorylation significantly decreased in NCX2(+/-) mouse hippocampus but increased in hippocampus of NCX3(+/-) mice. 29274751
2018-02-10 11:12:00 NCX2 (and NCX1) are expressed in neurons that regulate the motility of the gastric fundus. 26787195
2017-08-12 10:07:00 the functional role of NCX on gastrointestinal motility 27928109
2017-02-25 10:53:00 NCX1 and NCX2 play important roles in ileal motility and suggest that NCX1 and NCX2 regulate the motility in the ileum by controlling the sensitivity of smooth muscles to ACh and SP. 27411318
2017-02-18 11:16:00 The ability to solve elementary logic tasks in mice with the knockout of sodium-calcium exchanger gene 2 (NCX2). 27595821

名称对应

Type IDs
Synonymous Ncx2
Gene
UniProtKB-ID: NAC2_MOUSE
UniprotKB: Q8K596
UniParc: UPI0000028DD9, UPI0000419FE3
EMBL: AF503502, BC058704, BC080277, AC151733, CH466654, AB080745
Ensembl: ENSMUSG00000030376
KO: mmu:110891
Nucleutide sequences
EMBL-CDS: AAH58704.1, AAM22231.1, BAB85834.1, AAH80277.1, EDL42109.1
Ensembl_TRS: ENSMUST00000211649, ENSMUST00000168693
Protein sequencees
Ensembl_PRO: ENSMUSP00000147497, ENSMUSP00000128926
RefSeq: XP_006539534.1, NP_001334490.1, NP_683748.1
Others
UniRef100: UniRef100_Q8K596
UniRef90: UniRef90_Q8K596
UniRef50: UniRef50_Q8K596
UniGene: Mm.241147
CCDS: CCDS20845.1, CCDS85220.1

全选

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研究热度

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