| Type | Description |
|---|---|
| Definition | gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 12:12:00 | in CA1 somatostatin-expressing interneurons, the alpha5-GABAAR subunit is targeted to synapses formed by the VIP- and calretinin-expressing inputs, and plays a specific role in the regulation of anxiety-like behavior | 30523065 |
| 2019-10-12 11:00:00 | both total GABAA and GABAA alpha5 receptor availability in two positron emission tomography imaging studies, are reported. | 30282698 |
| 2019-03-02 12:31:00 | These results provide further evidence of the role of GABAA alpha5 receptor-mediated inhibition in cognitive impairment in the TS mouse model of Down syndrome. | 28717969 |
| 2019-01-26 12:14:00 | Nonlinear-rectifying alpha5-GABAARs with slow kinetics match functional NMDA-receptor properties and thereby mediate powerful control of dendritic postsynaptic integration and action potential firing by dendrite-targeting interneurons. | 30177704 |
| 2018-03-24 11:21:00 | findings support the hypothesis that reduced alpha5GABAAR activity contributes to an Autism Spectrum Disorder phenotype. The results also suggest that Gabra5-/- mice may serve as an animal model for ASD, as assessed through EEG activity and sleep-wake behaviors. | 27793660 |
| Type | IDs |
|---|---|
| Synonymous | A230018I05Rik |
| Gene |
UniProtKB-ID:
GBRA5_MOUSE
UniprotKB:
Q8BHJ7
UniParc:
UPI0000024C5C
EMBL:
AK038476,
BC062112,
AK083185
Ensembl:
ENSMUSG00000055078
KO:
mmu:110886
|
| Nucleutide sequences |
EMBL-CDS:
BAC38799.1,
BAC30012.1,
AAH62112.1
Ensembl_TRS:
ENSMUST00000206382,
ENSMUST00000068456,
ENSMUST00000206734
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000145685,
ENSMUSP00000063276,
ENSMUSP00000146238
RefSeq:
NP_001349090.1,
XP_006540619.1,
XP_006540623.1,
XP_006540620.1,
NP_001349091.1,
NP_795916.1,
XP_030097848.1
|
| Others |
UniRef100:
UniRef100_Q8BHJ7
UniRef90:
UniRef90_Q8BHJ7
UniRef50:
UniRef50_Q8BHJ7
UniGene:
Mm.273114
CCDS:
CCDS21322.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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