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11079 RER1

11079

RER1

retention in endoplasmic reticulum sorting receptor 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition retention in endoplasmic reticulum sorting receptor 1

研究结论

Date Results Publications
2019-04-13 11:42:00 The present study has demonstrated that enhances the progression of PC through promoting cell proliferation, migration and aggressiveness. 30630537
2019-01-19 11:39:00 Study in knockout mice and genetically modified human HAP1 cell line suggests that Rer1 maintains Notch signaling by maintaining sufficient expression of the gamma-secretase complex on the cell surface and regulating neural stem cell maintenance during cerebral cortex development. 30260951
2017-10-28 13:23:00 is a novel and potential important mediator of elevated alphaSyn levels 28877262
2015-10-31 11:18:00 Rer1p regulates the ER retention of immature or misfolded rhodopsin and modulates its intracellular trafficking through the early secretory pathway. 25096327
2015-10-24 10:22:00 Charcot-Marie-Tooth disease-related PMP22 is trapped in the endoplasmic reticulum by calnexin-dependent retention and Rer1-mediated early Golgi retrieval systems and partly degraded by the Hrd1-mediated endoplasmic reticulum-associated degradation system. 25385046

名称对应

Type IDs
Gene
UniProtKB-ID: RER1_HUMAN, Q5T094_HUMAN
UniprotKB: O15258, Q5T094
UniParc: UPI0000000C69
EMBL: BC004965, AK289658, CH471183, AF091071, BT007224, AJ001421
Ensembl: ENSG00000157916
KO: hsa:11079
Nucleutide sequences
EMBL-CDS: AAC72940.1, AAH04965.1, CAA04754.1, BAF82347.1, EAW56110.1, EAW56111.1, EAW56113.1, EAW56109.1, AAP35888.1
Gene_ORFName: hCG_24604
Ensembl_TRS: ENST00000605895, ENST00000488353
Protein sequencees
Ensembl_PRO: ENSP00000464222, ENSP00000475168
RefSeq: NP_008964.3
Others
UniRef100: UniRef100_O15258
UniRef90: UniRef90_O15258
UniRef50: UniRef50_O15258
UniGene: Hs.525527
CCDS: CCDS41232.1

全选

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研究热度

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