| Type | Description |
|---|---|
| Definition | tubulin polymerization promoting protein |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 10:04:00 | This study revealed the low expression level of TPPP in pancreatic cancer cells. In addition, the high expression of TPPP promotes the invasion, migration and angiogenesis of pancreatic cancer cells. | 31631174 |
| 2020-06-13 11:20:00 | These results demonstrate that TPPP on Golgi outposts are important for local microtubule nucleation and myelin sheath elongation. | 31522887 |
| 2020-03-21 11:44:00 | The binding of TPPP/p25 to a new binding site of DYNLL/LC8, outside the canonical binding groove, counteracted the TPPP/p25-derived hyperacetylation of the microtubule network. | 31505170 |
| 2018-12-22 12:31:00 | TPPP/p25 is co-enriched and co-localized with alpha-synuclein in brain inclusions of Parkinson's disease patients. Interaction of alpha-synuclein with various deletion mutants and fragments of TPPP/p25 were characterized. | 27671864 |
| 2018-10-20 11:58:00 | The objective of this paper is to highlight a critical point of a recently published Skoufias's paper in which the crucial role of the microtubules in TPPP/p25 dimerization leading to microtubule bundling was suggested. | 28074911 |
| Type | IDs |
|---|---|
| Synonymous | TPPP/p25, TPPP1, p24, p25, p25alpha |
| Gene |
UniProtKB-ID:
TPPP_HUMAN,
Q4L233_HUMAN
UniprotKB:
O94811,
Q4L233
UniParc:
UPI0000130FB2
EMBL:
BC152382,
AK054920,
BC131506,
BT020035,
AB017016,
BC040496,
AY319261,
CH471235
Ensembl:
ENSG00000171368
KO:
hsa:11076
|
| Nucleutide sequences |
EMBL-CDS:
AAV38838.1,
BAA36164.1,
AAH40496.1,
AAI52383.1,
BAG51443.1,
AAI31507.1,
EAW51015.1,
AAQ96657.1
Gene_ORFName:
hCG_16469
Ensembl_TRS:
ENST00000360578
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000353785
RefSeq:
XP_005248294.2,
NP_008961.1,
XP_024310114.1,
XP_016864482.1
|
| Others |
UniRef100:
UniRef100_O94811
UniRef90:
UniRef90_O94811
UniRef50:
UniRef50_O94811
UniGene:
Hs.481466
CCDS:
CCDS3856.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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