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11072 DUSP14

11072

DUSP14

dual specificity phosphatase 14

protein-coding

Homo sapiens

基因描述

Type Description
Definition dual specificity phosphatase 14

研究结论

Date Results Publications
2020-07-11 10:11:00 Bioinformatic studies showed that these two miRNAs target PTEN and DUSP14 tumor suppressor genes. Quantitative confirmed the overexpression of the miRNAs and downregulation of their targets. Luciferase assay confirmed that the miRNAs target PTEN and DUSP14. 30335891
2018-10-13 11:58:00 Hepatocyte DUSP14 is required for maintaining hepatic metabolic homeostasis and for suppressing inflammation, a novel function that relies on constraining TAK1 hyperactivation 29077210
2017-02-18 11:16:00 The AA genotype was associated with protection against active TB. Among disease-free individuals, T-helper type-1 related genes, IFNGR2 and mRNA levels significantly increased as the number of A alleles of rs1051838 increased. 26938665
2016-10-22 11:26:00 levels significantly decreased in failing hearts 26891723
2016-09-24 11:26:00 these findings reveal a novel mechanism by which TRAF2 mediates Lys63-linked ubiquitination of DUSP14, leading to DUSP14 activation in T cells 26521044

名称对应

Type IDs
Synonymous MKP-L, MKP6
Gene
UniProtKB-ID: DUS14_HUMAN, Q6FI36_HUMAN
UniprotKB: O95147, Q6FI36
UniParc: UPI0000129965
EMBL: AF038844, BC001894, AK314894, BC000370, CR541800, AF120032, CH471199, BC004448, CR536500
Ensembl: ENSG00000276023, ENSG00000275932
KO: hsa:11072
Nucleutide sequences
EMBL-CDS: AAH00370.1, AAH01894.1, AAD02105.1, AAH04448.1, AAF28861.1, EAW57592.1, CAG46599.1, BAG37408.1, EAW57593.1, CAG38739.1
Gene_ORFName: hCG_28185
Ensembl_TRS: ENST00000613659, ENST00000614411, ENST00000632468, ENST00000617516, ENST00000633870, ENST00000614294
Protein sequencees
Ensembl_PRO: ENSP00000484091, ENSP00000488882, ENSP00000477653, ENSP00000478595, ENSP00000478406, ENSP00000487886
RefSeq: NP_008957.1, XP_005257034.1, XP_011522536.1
Others
UniRef100: UniRef100_O95147
UniRef90: UniRef90_O95147
UniRef50: UniRef50_O95147
UniGene: Hs.91448
CCDS: CCDS11320.1

全选

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