| Type | Description |
|---|---|
| Definition | ribosomal protein S6 kinase polypeptide 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-09 12:30:00 | RSK2 mediates a procontractile signaling pathway that contributes to the regulation of basal vascular tone, myogenic vasoconstriction, and blood pressure | 30377223 |
| 2019-09-07 11:44:00 | Severe deficits were identified in spatial pattern separation in an Rsk2-deficient model of Coffin-Lowry syndrome. | 29627578 |
| 2019-02-09 11:58:00 | IL-10 induction in B cells was regulated by an ERK1/2- and p90 ribosomal S6 kinase-dependent mechanism, unlike in macrophages in which p90 ribosomal S6 kinase was not required. | 29229781 |
| 2019-01-26 11:07:00 | Rsk1 and Rsk2 protein levels are specifically reduced in the striatum of Huntington's disease mouse models at symptomatic stage. | 27063456 |
| 2018-10-27 12:08:00 | M-CSF-evoked ERK1/2 activation was decreased, whereas AKT activation was enhanced in SHP2-deficient BMMs. ERK1/2, via its downstream target RSK2, mediates this negative feedback by negatively regulating phosphorylation of M-CSF receptor at Tyr721 and, consequently, its binding to p85 subunit of PI3K and PI3K activation. | 29046360 |
| Type | IDs |
|---|---|
| Synonymous | MAPKAPK-1b, MPK-9, Rsk2, S6K-alpha3, p90RSK3, pp90RSK2 |
| Gene |
UniProtKB-ID:
KS6A3_MOUSE,
B1AXN9_MOUSE
UniprotKB:
P18654,
B1AXN9
UniParc:
UPI000012DB2F,
UPI00001F8680
EMBL:
AL671881,
AY083469,
AL808146
Ensembl:
ENSMUSG00000031309
KO:
mmu:110651
|
| Nucleutide sequences |
EMBL-CDS:
AAM00022.1
Ensembl_TRS:
ENSMUST00000033671,
ENSMUST00000112493
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000033671,
ENSMUSP00000108112
RefSeq:
XP_030107056.1,
XP_006528750.1,
NP_683747.1,
XP_006528751.1,
XP_036017675.1,
XP_030107058.1,
XP_017173844.1,
XP_036017676.1,
XP_017173843.1,
NP_001333604.1
|
| Others |
UniRef100:
UniRef100_B1AXN9,
UniRef100_P18654
UniRef90:
UniRef90_P51812
UniRef50:
UniRef50_P51812
UniGene:
Mm.328476
CCDS:
CCDS30502.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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