| Type | Description |
|---|---|
| Definition | LIM homeobox transcription factor 1 alpha |
| Date | Results | Publications |
|---|---|---|
| 2021-01-30 13:03:00 | Interaction with ectopic cochlear crista sensory epithelium disrupts basal cochlear sensory epithelium development in Lmx1a mutant mice. | 31932950 |
| 2020-01-04 11:02:00 | homeobox TF Lmx1a can activate the Cux2 enhancer through activation of a conserved intronic enhancer | 30770393 |
| 2019-10-19 10:54:00 | we provide genetic evidence that a transcription factor, Lmx1a, interacts with its negative regulator, Lmo4, to pattern various vestibular and auditory components of the mammalian inner ear. | 29769265 |
| 2019-03-30 11:04:00 | Homozygous Lmx1a mutant mice (Dreher) are deaf with dysmorphic ears with an abnormal morphogenesis and fused and misshapen sensory organs; however, computed tomography performed on a hearing-impaired family member did not reveal any cochleovestibular malformations. | 29971487 |
| 2018-02-10 10:29:00 | Data show that sustained expression of Lmx1a and Lmx1b is required for the survival of adult midbrain dopaminergic neurons. | 27407143 |
| Type | IDs |
|---|---|
| Synonymous | Lmx1.1, dr, dreher, sst |
| Gene |
UniProtKB-ID:
LMX1A_MOUSE,
Q543W2_MOUSE
UniprotKB:
Q9JKU8,
Q543W2
UniParc:
UPI0000004065
EMBL:
BC109168,
AF226662,
BC109167,
AK044944
Ensembl:
ENSMUSG00000026686
KO:
mmu:110648
|
| Nucleutide sequences |
EMBL-CDS:
AAF43012.1,
BAC32153.1,
AAI09169.1,
AAI09168.1
Ensembl_TRS:
ENSMUST00000111377,
ENSMUST00000028003
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000028003,
ENSMUSP00000107008
RefSeq:
XP_017177173.1,
XP_006496674.1,
XP_030097992.1,
NP_387501.1
|
| Others |
UniRef100:
UniRef100_Q9JKU8
UniRef90:
UniRef90_Q9JKU8
UniRef50:
UniRef50_Q9JKU8
UniGene:
Mm.330081
CCDS:
CCDS15460.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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