| Type | Description |
|---|---|
| Definition | glutamate receptor, ionotropic, kainate 4 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-02 11:16:00 | The cytoplasmic domain of the GluK2 low-affinity subunit stabilizes kainate receptors at synapses. In contrast, the extracellular domain of the GluK4/5 high-affinity subunit synergistically controls the synaptic specificity of kainate receptors through interaction with C1q-like proteins. | 27346345 |
| 2016-12-17 12:02:00 | These data reveal some requirements for kainate receptor targeting to the synapse, indicating a fundamental role of high affinity kainate receptor subunits in this process. | 25316333 |
| 2016-01-16 11:59:00 | This study demonstrated that mice overexpressing grik4 to directly address circuit dysfunctions associated with ASDs and test specific treatments of autism-related behaviors. | 26446216 |
| 2013-08-31 12:36:00 | we found that GluK4 is a key mediator of excitotoxic neurodegeneration | 23357115 |
| 2012-05-26 10:23:00 | This study demonstrated a clear anxiolytic and antidepressant phenotype associated with ablation of Grik4 and a parallel disruption in hippocampal plasticity. | 22203159 |
| Type | IDs |
|---|---|
| Synonymous | 6330551K01Rik, GluK4, GluRgamma1, KA-1, KA1 |
| Gene |
UniProtKB-ID:
GRIK4_MOUSE
UniprotKB:
Q8BMF5
UniParc:
UPI00001932AF
EMBL:
AC136903,
AC160123,
AC122449,
AK032029,
AC140387
Ensembl:
ENSMUSG00000032017
KO:
mmu:110637
|
| Nucleutide sequences |
EMBL-CDS:
BAC27660.1
Ensembl_TRS:
ENSMUST00000034515,
ENSMUST00000114865
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000034515,
ENSMUSP00000110515
RefSeq:
XP_006510005.1,
NP_780690.2,
XP_017168592.1,
XP_030099874.1,
XP_030099871.1,
XP_036010454.1,
XP_017168593.1,
XP_030099872.1,
XP_006510004.1,
XP_006510006.1,
XP_036010455.1,
XP_030099875.1,
XP_011240685.1
|
| Others |
UniRef100:
UniRef100_Q8BMF5
UniRef90:
UniRef90_Q8BMF5
UniRef50:
UniRef50_Q01812
UniGene:
Mm.370291
CCDS:
CCDS23089.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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