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11061 CNMD

11061

CNMD

chondromodulin

protein-coding

Homo sapiens

基因描述

Type Description
Definition chondromodulin

研究结论

Date Results Publications
2018-07-21 10:24:00 ChMI directly suppressed the proliferation and growth of osteosarcoma cells. 28983591
2018-06-02 10:28:00 CHM1 seems to have pleiotropic functions in Ewing sarcoma. 28319320
2017-02-25 12:21:00 The results of the present study indicated that ChMI was able to inhibit the growth of breast cancer cells; thus suggesting that ChM-I may have potential clinical applications in the treatment of breast cancer. 27035228
2016-05-21 10:48:00 Data suggest ChM1 as potential tumor suppressor in gastric cancer and useful biomarker for the treatment and prognosis. Its expression was downregulated in cancer tissue, and correlated with advanced stages, lymph node metastasis, and poorer prognosis. 26165347
2014-12-06 12:59:00 intact 20-25 kDa ChM-I is stored as a component of extracellular matrix in the avascular cartilage zones, but it is inactivated by a single N-terminal proteolytic cleavage in the hypertrophic zone of growth-plate cartilage 24710035

名称对应

Type IDs
Synonymous BRICD3, CHM-I, CHM1, LECT1, MYETS1
Gene
UniProtKB-ID: CNMD_HUMAN
UniprotKB: O75829
UniParc: UPI000006FCED, UPI000003F666
EMBL: AF050147, AL139085, AB005999, AL139089, AB021290, AB006000, CR541910, BC025659
Ensembl: ENSG00000136110
KO: hsa:11061
Nucleutide sequences
EMBL-CDS: BAA33443.1, AAC98971.1, CAG46708.1, BAA86262.1, BAA77384.1, AAH25659.1
Ensembl_TRS: ENST00000377962, ENST00000448904
Protein sequencees
Ensembl_PRO: ENSP00000388576, ENSP00000367198
RefSeq: NP_001011705.1, XP_011533199.1, XP_011533200.1, XP_011533201.1, NP_008946.1, XP_011533202.1
Others
UniRef100: UniRef100_O75829
UniRef90: UniRef90_O75829
UniRef50: UniRef50_O75829
UniGene: Hs.421391
CCDS: CCDS45051.1, CCDS9437.1

全选

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