| Type | Description |
|---|---|
| Definition | farnesyltransferase, CAAX box, beta |
| Date | Results | Publications |
|---|---|---|
| 2016-03-26 10:49:00 | the catalytic b subunit of farnesyl transferase associated with a cytoskeletal protein...lonafarnib remarkably inhibited he expression of the cytoskeletal protein and interrupted its interaction with farnesyl transferase. | 25853815 |
| 2014-12-20 11:39:00 | Data suggest that farnesyltransferase might constitute a target in the management of severe acute pancreatitis (AP). | 24622074 |
| 2012-04-14 10:49:00 | deficiencies in either FTase or GGTase-I lead to severe hepatocellular disease. Our studies lay to rest the earlier notion that FTase is dispensable in adult tissues | 22039581 |
| 2010-09-20 11:28:00 | Both Fntb and Pggt1b are required for the homeostasis of skin keratinocytes. | 20106865 |
| 2010-01-21 00:00:00 | FTase is essential for embryonic development, but dispensable for adult homeostasis. Elimination of FTase during tumor progression had a limited but significant inhibitory effect on tumor development. | 15837621 |
| Type | IDs |
|---|---|
| Synonymous | 2010013E13Rik, AA409500 |
| Gene |
UniProtKB-ID:
FNTB_MOUSE
UniprotKB:
Q8K2I1
UniParc:
UPI00000286EE
EMBL:
BC031417
Ensembl:
ENSMUSG00000033373
KO:
mmu:110606
|
| Nucleutide sequences |
EMBL-CDS:
AAH31417.1
Ensembl_TRS:
ENSMUST00000041008
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000035498
RefSeq:
XP_006515467.1,
NP_666039.1
|
| Others |
UniRef100:
UniRef100_Q8K2I1
UniRef90:
UniRef90_P49356
UniRef50:
UniRef50_P49356
UniGene:
Mm.151174
CCDS:
CCDS25998.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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