| Type | Description |
|---|---|
| Definition | Rho guanine nucleotide exchange factor (GEF) 28 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-01 13:12:00 | A new role for Rgnef in ovarian cancer to facilitate NF-kappaB-mediated gene expression protecting cells from oxidative stress. | 31308489 |
| 2018-04-28 10:42:00 | observed that the expression of RGNEF is upregulated in murine spinal motor neurons following distal sciatic nerve injury | 28495450 |
| 2014-06-07 12:57:00 | Rgnef promotes integrin beta 1-stimulated focal adhesion kinase activation. | 24006257 |
| 2012-10-13 10:38:00 | An essential role for Rgnef in RhoA regulation downstream of integrins in control of cell migration. | 22649559 |
| 2010-01-21 00:00:00 | represents an essential effector pathway of Rho GTPases in regulating multiple cellular functions including actin cytoskeleton reorganization, cell migration, gene activation, and proliferation | 15705584 |
| Type | IDs |
|---|---|
| Synonymous | 9230110L08Rik, AI323540, D13Bwg1089e, RIP2, Rgnef, RhoGEF, Rhoip2, p190RhoGEF |
| Gene |
UniProtKB-ID:
ARG28_MOUSE,
G5E8P2_MOUSE,
A0A571BEH9_MOUSE
UniprotKB:
P97433,
G5E8P2,
A0A571BEH9
UniParc:
UPI0000194B98,
UPI0001663053,
UPI0003D76BF4,
UPI0000028F5F
EMBL:
AC123056,
BC022978,
AC124397,
AC133507,
U73199,
BC075734,
AK173325
Ensembl:
ENSMUSG00000021662
KO:
mmu:110596
|
| Nucleutide sequences |
EMBL-CDS:
AAH75734.1,
AAB18197.1,
AAH22978.1,
BAD32603.1
Ensembl_TRS:
ENSMUST00000109426,
ENSMUST00000238746
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000105053,
ENSMUSP00000158740
RefSeq:
XP_006517585.1,
XP_017170850.1,
XP_036013727.1,
XP_006517584.1,
XP_006517581.1,
NP_036156.2,
XP_017170851.2,
XP_006517582.1
|
| Others |
UniRef100:
UniRef100_P97433,
UniRef100_A0A571BEH9,
UniRef100_G5E8P2
UniRef90:
UniRef90_P97433
UniRef50:
UniRef50_P97433
UniGene:
Mm.252718
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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