| Type | Description |
|---|---|
| Definition | WW domain containing E3 ubiquitin protein ligase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:56:00 | [Abnormal expression of WWP1 in chronic lymphocytic leukemia and its clinical significance]. | 33113605 |
| 2020-06-06 12:45:00 | n this study involving patients with disorders resulting in a predisposition to the development of multiple malignant neoplasms without PTEN germline mutations, we confirmed the function of WWP1 as a cancer-susceptibility gene through direct aberrant regulation of the PTEN-PI3K signaling axis. | 32459922 |
| 2020-03-21 12:23:00 | WWP1 overexpression decreased miR-30a-5p expression and inhibited glioma cell malignant behaviors via inhibiting NF-kappaB p65. | 30978403 |
| 2020-02-15 10:09:00 | RT-qPCR and Western blot showed that WWP1 was positively regulated by SNHG12 and negatively regulated by miR-129-5p at the mRNA level and protein level. Overexpression of WWP1 significantly increased proliferation and invasion of laryngeal cancer cells. | 31348766 |
| 2019-02-23 12:58:00 | Provide molecular insights into the anti-cancer potential of WWP1 inhibition. | 29209041 |
| Type | IDs |
|---|---|
| Synonymous | AIP5, Tiul1, hSDRP1 |
| Gene |
UniProtKB-ID:
WWP1_HUMAN
UniprotKB:
Q9H0M0
UniParc:
UPI0000035537,
UPI00001AAC5A,
UPI00001AAC59,
UPI00001AAC5B
EMBL:
AC083845,
AY345857,
BC015380,
BC036065,
AC103817,
U96113,
AY043361,
AL136739
Ensembl:
ENSG00000123124
KO:
hsa:11059
|
| Nucleutide sequences |
EMBL-CDS:
AAQ22764.1,
CAB66673.1,
AAK94668.1,
AAC51324.1,
AAH15380.2,
AAH36065.1
Ensembl_TRS:
ENST00000517970,
ENST00000265428
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000427793,
ENSP00000265428
RefSeq:
XP_016868483.1,
XP_016868484.1,
XP_005250817.1,
NP_008944.1,
XP_016868486.1,
XP_016868485.1,
XP_016868482.1,
XP_024302824.1,
XP_005250818.1
|
| Others |
UniRef100:
UniRef100_Q9H0M0
UniRef90:
UniRef90_Q9H0M0
UniRef50:
UniRef50_Q9H0M0
UniGene:
Hs.655189
CCDS:
CCDS6242.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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