| Type | Description |
|---|---|
| Definition | abhydrolase domain containing 2 |
| Date | Results | Publications |
|---|---|---|
| 2018-03-03 11:32:00 | Suppression of ABHD2 in OVCA420 cells increased phosphorylated p38 and ERK, platinum resistance, and side population cells (p<0.01, respectively). Conversely, overexpression of ABHD2 decreased resistance to anoikis (p<0.05) and the amount of phosphorylated p38 and ERK in OVCA420 and SKOV3 cells. | 27323405 |
| 2017-12-09 13:39:00 | A mutant ABHD2 developed with alanine in place of Ser(207). | 27247428 |
| 2017-08-26 11:56:00 | These results show that joint tests of main effects and gene-gene interaction reveal associations at some novel loci that were missed when considering main effects alone. | 28813576 |
| 2016-06-04 10:18:00 | ABHD2 gene single nucleotide polymorphisms, such as rs12442260 contribute to chronic obstructive pulmonary disease susceptibility in the Chinese Han population. | 25880496 |
| 2016-05-14 12:04:00 | ABHD2 is highly expressed in spermatozoa, binds progesterone, and acts as a progesterone-dependent lipid hydrolase by depleting the endocannabinoid 2-arachidonoylglycerol (2AG) from plasma membrane. | 26989199 |
| Type | IDs |
|---|---|
| Synonymous | HS1-2, LABH2, PHPS1-2 |
| Gene |
UniProtKB-ID:
ABHD2_HUMAN,
A0A024RC89_HUMAN
UniprotKB:
P08910,
A0A024RC89
UniParc:
UPI000012E24E
EMBL:
AK222841,
BC019248,
HM005319,
AK223083,
AF546700,
CH471101,
BC090052,
X12433
Ensembl:
ENSG00000140526
KO:
hsa:11057
|
| Nucleutide sequences |
EMBL-CDS:
BAD96561.1,
AAH19248.1,
BAD96803.1,
CAA30976.1,
AAH90052.1,
AAQ12021.1,
EAX02033.1,
EAX02035.1,
EAX02034.1,
AEE60919.1
Gene_ORFName:
hCG_28637
Ensembl_TRS:
ENST00000565973,
ENST00000352732
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000268129,
ENSP00000455639
RefSeq:
NP_690888.1,
XP_005254890.1,
XP_024305600.1,
XP_024305597.1,
XP_024305599.1,
XP_024305598.1,
XP_011519467.1,
XP_024305602.1,
NP_008942.3,
XP_005254889.1
|
| Others |
UniRef100:
UniRef100_P08910
UniRef90:
UniRef90_P08910
UniRef50:
UniRef50_P08910
UniGene:
Hs.122337
CCDS:
CCDS10348.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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