| Type | Description |
|---|---|
| Definition | acetyl-Coenzyme A acetyltransferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 11:45:00 | findings provide detailed insights into the role of free cholesterol in LD and adipocyte function and suggest that ACAT inhibitors have potential utility for managing disorders associated with extreme obesity | 31727739 |
| 2019-02-02 10:56:00 | A Soat1 deletion present in AKR mice, and resultant N-terminal ACAT1 truncation, was confirmed to be a significant modifier of macrophage cholesterol metabolism. | 29097366 |
| 2017-02-04 10:47:00 | Data show that microRNA miR-467b regulates the acetyl-CoA acetyltransferase 1 (ACAT1) expression via targeting ACAT1 3' untranslated regions (3'UTR). | 27678191 |
| 2016-08-13 10:21:00 | In a mouse model, targeting ACAT1 specifically in a myeloid lineage may benefit atherosclerosis progression by reducing the infiltration of foamy macrophages. | 26801614 |
| 2016-04-30 11:32:00 | Its blockage enhances autophagy of and reduces human p301L-tau content in brain neurons of pre-symptomatic stage of Alzheimer disease. | 25930235 |
| Type | IDs |
|---|---|
| Synonymous | 6330585C21Rik, Acat |
| Gene |
UniProtKB-ID:
THIL_MOUSE
UniprotKB:
Q8QZT1
UniParc:
UPI0000023979
EMBL:
AK169771,
AK032097,
AJ510150,
BC024763,
AK081715
Ensembl:
ENSMUSG00000032047
KO:
mmu:110446
|
| Nucleutide sequences |
EMBL-CDS:
CAD52869.1,
BAC27697.1,
AAH24763.1,
BAE41356.1,
BAC38304.1
Ensembl_TRS:
ENSMUST00000034547
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000034547
RefSeq:
NP_659033.1
|
| Others |
UniRef100:
UniRef100_Q8QZT1
UniRef90:
UniRef90_P17764
UniRef50:
UniRef50_P17764
UniGene:
Mm.293233
CCDS:
CCDS23184.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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