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1104 RCC1

1104

RCC1

regulator of chromosome condensation 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition regulator of chromosome condensation 1

研究结论

Date Results Publications
2021-04-03 13:36:00 PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells. 33539787
2019-11-09 11:53:00 cyclin-dependent kinase 1 (Cdk1), a known target of E2F1, is involved in G1 checkpoint regulation, as Cdk1 knockdown hindered G1/S progression, while Cdk1 overexpression rescued RCC1 knockdown-mediated effect on G1 cell cycle progression. 29789527
2019-09-14 10:14:00 RCC1 regulates KT composition at the metaphase-anaphase transition in a Ran-GTP independent fashion through displacement of Shugoshin-1 and chromosomal passenger complex. 29464982
2018-12-22 11:36:00 This study provides first evidence for a mutation in RCC1 as a breast cancer susceptibility allele 29363114
2018-04-21 10:11:00 Importin alpha3 facilitates the nuclear transport of the Ran guanine nucleotide exchange factor RCC1. 29042532

名称对应

Type IDs
Synonymous CHC1, RCC1-I, SNHG3-RCC1
Gene
UniProtKB-ID: RCC1_HUMAN, A0A0S2Z404_HUMAN, Q5T081_HUMAN, A0A0S2Z3I4_HUMAN
UniprotKB: P18754, A0A0S2Z404, Q5T081, A0A0S2Z3I4
UniParc: UPI0000001660, UPI0000204066, UPI0000E26242
EMBL: BC010067, S75708, X12654, KU177975, BC007300, CH471059, CR407693, BC069198, AF498924, X06130, KU177974, BC036903, D00591, KU177976
Ensembl: ENSG00000180198
KO: hsa:1104
Nucleutide sequences
EMBL-CDS: AAB32653.1, AAM21072.1, AAH07300.1, CAA31182.1, AAH10067.1, AAH36903.1, BAA00469.1, AAH69198.1, CAA29496.1, ALQ33433.1, CAG28621.1, EAX07693.1, ALQ33432.1, EAX07691.1, ALQ33434.1
Gene_ORFName: hCG_27809
Ensembl_TRS: ENST00000373832, ENST00000373831, ENST00000398958, ENST00000373833, ENST00000649185
Protein sequencees
Ensembl_PRO: ENSP00000362937, ENSP00000497402, ENSP00000362939, ENSP00000362938, ENSP00000381931
RefSeq: NP_001368795.1, NP_001368794.1, NP_001260.1, NP_001041660.1, NP_001041664.1, NP_001041659.1
Others
UniRef100: UniRef100_P18754, UniRef100_P18754-2, UniRef100_A0A0S2Z3I4
UniRef90: UniRef90_P18754
UniRef50: UniRef50_P18754
UniGene: Hs.469723
CCDS: CCDS323.1, CCDS41295.1

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