| Type | Description |
|---|---|
| Definition | destrin, actin depolymerizing factor |
| Date | Results | Publications |
|---|---|---|
| 2016-09-17 10:05:00 | analysis of human Cof1, Cof2, and ADF effects on actin filament severing and turnover | 26996939 |
| 2013-01-12 10:49:00 | Destrin is upregulated in nerve-invasive pancreatic cancer cells and its expression might be related to perineural invasiveness | 22898637 |
| 2011-07-16 11:30:00 | The ADF/cofilin1-dependent severing of actin filaments exposes and promotes the activation of SPCA1, which pumps Ca(2+) into the lumen of the TGN for the sorting of the class of secretory cargo that binds Ca(2+). | 21571222 |
| 2011-03-12 11:26:00 | Changes in the expression of cytoskeletal regulatory proteins such as LIMK and cofilin may play a role in weakening thoracic aortic medial tissue, as a precondition to thoracic aortic dissection. | 20873970 |
| 2010-10-23 11:10:00 | The results of this study suggested that temporally regulated ADF/cofilin activities function in postsynaptic modifications of receptor number and spine size during synaptic plasticity. | 20835250 |
| Type | IDs |
|---|---|
| Synonymous | ACTDP, ADF, HEL32, bA462D18.2 |
| Gene |
UniProtKB-ID:
DEST_HUMAN,
V9HWA6_HUMAN
UniprotKB:
P60981,
V9HWA6
UniParc:
UPI00001291DE,
UPI00004A67B3
EMBL:
GQ900922,
CR457042,
AL132765,
EU794606,
CH471133,
S65738,
AK312645,
BC009477,
AK302338
Ensembl:
ENSG00000125868
KO:
hsa:11034
|
| Nucleutide sequences |
EMBL-CDS:
CAG33323.1,
BAG63668.1,
EAX10275.1,
AAH09477.1,
AAB28361.1,
BAG35529.1,
EAX10276.1,
EAX10274.1,
ACJ13660.1,
ADO22439.1
Ensembl_TRS:
ENST00000474024,
ENST00000246069
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000246069,
ENSP00000476975
RefSeq:
NP_006861.1,
NP_001011546.1,
XP_011527446.1
|
| Others |
UniRef100:
UniRef100_P60981
UniRef90:
UniRef90_P60981
UniRef50:
UniRef50_Q9Y281
UniGene:
Hs.304192,
Hs.705996
CCDS:
CCDS13127.1,
CCDS46580.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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