| Type | Description |
|---|---|
| Definition | ArfGAP with dual PH domains 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 10:25:00 | Adap1 deletion in tumor cells ameliorated the basement membrane breakdown and had less invading cells in the stroma. Study demonstrates that ADAP1 is a critical mediator of TGF-beta-induced cancer invasion. | 31792062 |
| 2018-11-24 11:37:00 | Analyzed ArfGAP with dual PH domains 1 (ADAP1) using mass spectrometry and found that ADAP1 is phosphorylated at Y364. | 29659066 |
| 2015-06-27 10:07:00 | This review highlights the functions of the neuron-specific protein ADAP1 in neuronal differentiation and neurodegenerative diseases, with an overview of structural and biochemical properties of ADAP1. [review] | 24854535 |
| 2013-02-02 10:58:00 | SH-SY5Y cells, stably transfected with GFP-tagged-p42(IP4), show an enhanced NRD protein expression already at an earlier time point after retinoic acid stimulation. | 21801775 |
| 2012-02-25 10:58:00 | Tubulin potentiates the interaction of the metalloendopeptidase nardilysin with the neuronal scaffold protein p42IP4/centaurin-alpha1 (ADAP1). | 21972134 |
| Type | IDs |
|---|---|
| Synonymous | CENTA1, GCS1L, p42IP4 |
| Gene |
UniProtKB-ID:
ADAP1_HUMAN,
B4DUZ7_HUMAN,
A8K3A2_HUMAN
UniprotKB:
O75689,
B4DUZ7,
A8K3A2
UniParc:
UPI000013D694,
UPI00015DA772,
UPI00017A7D53,
UPI000022CDE8,
UPI0001AE701D
EMBL:
CH471144,
AC073957,
AJ006422,
AF082324,
AK290517,
CH236965,
AK300859,
AK300999,
BC033747,
AK092471,
AB097049
Ensembl:
ENSG00000105963
KO:
hsa:11033
|
| Nucleutide sequences |
EMBL-CDS:
BAC77402.1,
BAG62618.1,
EAW87183.1,
AAH33747.1,
EAW87184.1,
EAL23709.1,
CAA07024.1,
BAG52556.1,
AAD11414.1,
BAG62509.1,
BAF83206.1
Ensembl_TRS:
ENST00000539900,
ENST00000449296,
ENST00000611167,
ENST00000265846
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000442682,
ENSP00000407267,
ENSP00000265846,
ENSP00000481154
RefSeq:
NP_001271239.1,
NP_006860.2,
NP_001271238.2,
NP_001271240.2,
NP_001271237.1
|
| Others |
UniRef100:
UniRef100_O75689,
UniRef100_B4DUZ7,
UniRef100_A8K3A2
UniRef90:
UniRef90_A0A2I3REX3,
UniRef90_A0A087WTN6,
UniRef90_O75689
UniRef50:
UniRef50_O75689,
UniRef50_O75689-2,
UniRef50_A0A087WTN6
UniGene:
Hs.602573
CCDS:
CCDS5318.1,
CCDS64577.1,
CCDS64576.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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