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11031 RAB31

11031

RAB31

RAB31, member RAS oncogene family

protein-coding

Homo sapiens

基因描述

Type Description
Definition RAB31, member RAS oncogene family

研究结论

Date Results Publications
2020-09-19 16:28:00 Upregulation of Rab31 is associated with poor prognosis and promotes colorectal carcinoma proliferation via the mTOR/p70S6K/Cyclin D1 signalling pathway. 32707053
2019-11-02 10:58:00 The impaired EGFR signaling and its effects on epidermal differentiation were also observed in familial AI patients and Ncstn(DeltaKC) mice. Thus, our study showed that miR-30a-3p/RAB31/EGFR signaling pathway may play a key role in the pathogenesis of familial AI with NCSTN mutations. 30120935
2019-08-31 13:15:00 RAB31 plays an important role in osteosarcoma development. 30470957
2019-05-18 12:07:00 Findings identified a breast cancer (BC) susceptibility SNP, rs6506689 G>T in RAB31. Functional analysis of this germline mutation suggested that the rs6506689-T allele may increase FOXA1-binding affinity and up-regulates the expression of RAB31, ultimately promoting the development of BC. 30182384
2018-01-13 11:26:00 the role of Rab31 in cancer progression, is reported. 26245486

名称对应

Type IDs
Synonymous Rab22B
Gene
UniProtKB-ID: RAB31_HUMAN
UniprotKB: Q13636
UniParc: UPI0000001269
EMBL: CR407659, AP000902, AF234995, BC001148, U59877, BT020028, AF498957, U57091, BT020027, AK314809, AF183421, AC006238
Ensembl: ENSG00000168461
KO: hsa:11031
Nucleutide sequences
EMBL-CDS: AAV38831.1, AAH01148.1, AAC50773.1, BAG37334.1, AAG09690.1, CAG28587.1, AAB02832.1, AAV38830.1, AAG13847.1, AAM21105.1
Ensembl_TRS: ENST00000578921
Protein sequencees
Ensembl_PRO: ENSP00000461945
RefSeq: XP_016881018.1, NP_006859.2, XP_016881017.1
Others
UniRef100: UniRef100_Q13636
UniRef90: UniRef90_Q13636
UniRef50: UniRef50_Q13636
UniGene: Hs.99528, Hs.744887

全选

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研究热度

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