| Type | Description |
|---|---|
| Definition | breakpoint cluster region |
| Date | Results | Publications |
|---|---|---|
| 2021-02-02 13:24:00 | CRISPR/CAS9-mediated knockout of Abi1 inhibits p185(Bcr-Abl)-induced leukemogenesis and signal transduction to ERK and PI3K/Akt pathways. | 32276588 |
| 2020-05-23 12:43:00 | Authors have deleted the STK domain and mutated the critical Y177 residue and demonstrate that the transforming activity of these mutated genes is reduced compared to the BCR-FGFR1 parental kinase. In addition, we demonstrate that deletion of the FGFR1 tyrosine kinase domain abrogates transforming ability, which is not compensated for by BCR STK activity. | 31525277 |
| 2020-02-22 12:48:00 | Rather, BAI1 associates with the Rho-GTPase regulatory protein Bcr late in development and stimulates its cryptic RhoA-GEF activity, which functions together with its Rac1-GAP activity to terminate dendritic arborization. | 31461398 |
| 2020-02-08 10:40:00 | These results show that toll-like receptor-mediated signals support participation of B-1 cells in immune defense via BCR-complex reorganization. | 31433296 |
| 2019-10-26 12:20:00 | Loss of the BCR-FGFR1 GEF Domain Suppressing RHOA Activation is associated with enhanced B-Lymphomagenesis. | 30413411 |
| Type | IDs |
|---|---|
| Synonymous | 5133400C09Rik, AI561783, AI853148, mKIAA3017 |
| Gene |
UniProtKB-ID:
BCR_MOUSE,
A2RRK7_MOUSE
UniprotKB:
Q6PAJ1,
A2RRK7
UniParc:
UPI00006064D6,
UPI0000F059D5
EMBL:
BC060270,
BC131682,
AC160402,
X52831,
AK129482,
BC002193
Ensembl:
ENSMUSG00000009681
KO:
mmu:110279
|
| Nucleutide sequences |
EMBL-CDS:
BAC98292.1,
AAH60270.1,
CAA37013.1,
AAH02193.1,
AAI31683.1
Ensembl_TRS:
ENSMUST00000164107
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000126377
RefSeq:
XP_006513124.1,
NP_001074881.1,
XP_006513123.1
|
| Others |
UniRef100:
UniRef100_Q6PAJ1
UniRef90:
UniRef90_Q6PAJ1
UniRef50:
UniRef50_P11274
UniGene:
Mm.333722
CCDS:
CCDS35935.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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