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11027 LILRA2

11027

LILRA2

leukocyte immunoglobulin like receptor A2

protein-coding

Homo sapiens

基因描述

Type Description
Definition leukocyte immunoglobulin like receptor A2

研究结论

Date Results Publications
2021-01-16 15:54:00 Molecular mechanism of the recognition of bacterially cleaved immunoglobulin by the immune regulatory receptor LILRA2. 32424043
2018-02-03 11:54:00 findings demonstrate that LILRA2 is a type of innate immune receptor in the host immune system that detects immunoglobulin abnormalities caused by microbial pathogens. 27572839
2016-09-19 08:27:00 LILRA2 recognizes microbially cleaved antibodies and activates innate immunity, suggesting that LILRA2 detects dangerous immunological situations in which antibodies are destroyed by pathogens. 27572839
2012-11-24 10:38:00 LILRA2-mediated activation of monocytes is significantly different to LPS and that LILRA2 selectively modulates LPS-mediated monocyte activation and FcgammaRI-dependent phagocytosis. 22479404
2010-04-07 21:39:00 Observational study of gene-disease association. (HuGE Navigator) 20237496

名称对应

Type IDs
Synonymous CD85H, ILT1, LIR-7, LIR7
Gene
UniProtKB-ID: LIRA2_HUMAN, A8MZH0_HUMAN
UniprotKB: Q8N149, A8MZH0
UniParc: UPI00034F238C, UPI000189A3E0, UPI0000034C01, UPI000004984B, UPI000189A3E1
EMBL: EU915609, AC245036, BC027916, AF025531, BC017412, EU915610
Ensembl: ENSG00000239998, ENSG00000274000, ENSG00000278634, ENSG00000275290
KO: hsa:11027
Nucleutide sequences
EMBL-CDS: ACK56075.1, AAB87665.1, AAH27916.1, AAH17412.1, ACK56076.1
Ensembl_TRS: ENST00000617409, ENST00000251377, ENST00000620279, ENST00000616629, ENST00000391738, ENST00000621721, ENST00000251376, ENST00000611940, ENST00000613573, ENST00000622640, ENST00000391737
Protein sequencees
Ensembl_PRO: ENSP00000481338, ENSP00000479743, ENSP00000479914, ENSP00000480939, ENSP00000251376, ENSP00000483906, ENSP00000484762, ENSP00000375618, ENSP00000478981, ENSP00000251377, ENSP00000375617
RefSeq: XP_011524693.1, XP_011524688.1, XP_011524692.1, XP_016881713.1, NP_001124389.2, XP_011524687.1, XP_011524691.1, XP_006723049.1, NP_001277200.1, XP_011524689.1, XP_011524690.1, NP_001277199.1, NP_006857.2
Others
UniRef100: UniRef100_Q8N149, UniRef100_A8MZH0
UniRef90: UniRef90_Q8N149
UniRef50: UniRef50_Q8NHL6-5
UniGene: Hs.655593
CCDS: CCDS46179.1, CCDS12900.1

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