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110265 Msra

110265

Msra

methionine sulfoxide reductase A

protein-coding

Mus musculus

基因描述

Type Description
Definition methionine sulfoxide reductase A

研究结论

Date Results Publications
2021-01-23 12:57:00 MsrA Suppresses Inflammatory Activation of Microglia and to Prevent Demyelination via Inhibition of the NOX2-MAPKs/NF-kappaB Signaling Pathway. 32308370
2019-09-28 10:17:00 It has been proposed that MsrA-dependent 14-3-3 zeta ubiquitination affects the regulation of alpha synuclein degradation and dopamine synthesis in the brain. 30096435
2019-06-01 11:56:00 MsrA knockout mice showed an increased sensitivity to noise at young and older ages, suggesting that MsrA is part of a mechanism that protects the cochlea from acoustic damage. MsrA mRNA in the cochlea was increased following acoustic stimulation. 29929200
2018-10-13 11:31:00 Our findings demonstrate that reversal of methionine oxidation is required for maintenance of cellular homeostasis in the absence of increased oxidative stress. These data provide the first link between autophagy and activation of Nrf2 in the setting of MsrA deletion 29649787
2018-03-17 11:48:00 Study shows that cisplatin induces methionine oxidation, oxidative stress, mitochondrial damage, apoptosis, and necrosis, and that MsrA gene deletion accelerates these cisplatin-induced damages. This indicates that MsrA protects kidney against cisplatin-induced acute kidney injury. 28158949

名称对应

Type IDs
Synonymous 2310045J23Rik, 6530413P12Rik, MSR-A
Gene
UniProtKB-ID: MSRA_MOUSE, A0A1B0GT40_MOUSE
UniprotKB: Q9D6Y7, A0A1B0GT40
UniParc: UPI00020F7A54, UPI0000025E48, UPI0000021D8B, UPI0003D76B61, UPI00001E9146
EMBL: AC134898, CH466535, AK018338, AK009822, AC166997, AK049714, BC014738, AK002356, AC154332, BC089311
Ensembl: ENSMUSG00000054733
KO: mmu:110265
Nucleutide sequences
EMBL-CDS: BAB26522.1, AAH89311.1, AAH14738.1, BAB22035.1, BAC33889.1, EDL36048.1
Ensembl_TRS: ENSMUST00000210428, ENSMUST00000067927, ENSMUST00000210363
Protein sequencees
Ensembl_PRO: ENSMUSP00000147689, ENSMUSP00000065754, ENSMUSP00000148189
RefSeq: XP_011243223.1, NP_001240643.1, NP_080598.2, NP_001240645.1, NP_001334568.1, XP_030103466.1, XP_030103468.1, NP_001240641.1, NP_001240644.1, XP_030103467.1
Others
UniRef100: UniRef100_Q9D6Y7
UniRef90: UniRef90_Q9D6Y7
UniRef50: UniRef50_Q9UJ68
UniGene: Mm.26713
CCDS: CCDS27209.1, CCDS84147.1

全选

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