Type | Description |
---|---|
Definition | activating transcription factor 7 |
Date | Results | Publications |
---|---|---|
2019-05-18 12:37:00 | Results found that ATF7 is upregulated in hepatocellular carcinoma (HCC) tissue. Its expression is regulated by miR-340 which directly binds to the mRNA encoding ATF7. Under HBV infection, miR-340 is downregulated resulting in increasing ATF7 expression, leading to enhanced cell proliferation and inhibition of apoptosis. | 30891870 |
2018-11-03 10:38:00 | ATF7 is a direct target of miR-103a-3p. In a stomach cancer cohort,miR-103a-3p expression was inversely correlated with ATF7 expression. Silencing ATF7 showed similar cellular and molecular effects as miR-103a-3p overexpression, namely, increased GC cell proliferation, improved CDK2 expression and decreased P27 expression. | 29754469 |
2017-09-30 11:39:00 | knockdown of the mammalian homologs of PDK1 and ATF7 in HEK293 cells resulted in changes in metallothionein expression, suggesting that this pathway was evolutionarily conserved | 28632756 |
2016-08-20 11:43:00 | CARMA1- and MyD88-dependent activation of Jun/ATF-type AP-1 complexes is a hallmark of ABC diffuse large B-cell lymphomas. | 26747248 |
2016-05-28 12:20:00 | mitotic stabilized ATF7 protein re-localizes onto chromatin at the end of telophase and contributes to induce the cyclin D1 gene expression. | 26101806 |
Type | IDs |
---|---|
Synonymous | ATFA |
Gene |
UniProtKB-ID:
ATF7_HUMAN
UniprotKB:
P17544
UniParc:
UPI000002A477,
UPI0000161877,
UPI00000724F9,
UPI0000126230,
UPI0000D49DED,
UPI000002A476
EMBL:
BC140006,
AK298853,
BC042363,
CH471054,
AC073594,
X52943,
X57197,
AC023509,
BC136302
Ensembl:
ENSG00000170653
KO:
hsa:11016
|
Nucleutide sequences |
EMBL-CDS:
AAI36303.1,
EAW96724.1,
CAA40483.1,
AAI40007.1,
BAG60976.1,
EAW96723.1,
CAA37118.1,
AAH42363.1
Ensembl_TRS:
ENST00000456903,
ENST00000420353,
ENST00000548446,
ENST00000548118,
ENST00000591397
|
Protein sequencees |
Ensembl_PRO:
ENSP00000399465,
ENSP00000449938,
ENSP00000465192,
ENSP00000456858,
ENSP00000387406
RefSeq:
NP_001353485.1,
NP_001353491.1,
NP_001193611.1,
NP_001123532.1,
NP_001353490.1,
NP_001353484.1,
NP_001353487.1,
NP_001353492.1,
NP_006847.1,
NP_001193612.1
|
Others |
UniRef100:
UniRef100_P17544
UniRef90:
UniRef90_P17544
UniRef50:
UniRef50_P17544
UniGene:
Hs.12286,
Hs.633602
CCDS:
CCDS58238.1,
CCDS44906.1
|
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Refseq |
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