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110066 Tcrd

110066

Tcrd

T cell receptor delta chain

protein-coding

Mus musculus

基因描述

Type Description
Definition T cell receptor delta chain

研究结论

Date Results Publications
2018-07-28 11:46:00 This study demonstrated that LPS exposure induced reductions in white matter tissue volume in WT and Tcralpha (-/-) mice, but not in the Tcrd (-/-) mice, suggested that gammadeltaT cells but not alphabetaT cells contribute to sepsis-induced white matter injury and subsequent motor function abnormalities in early life. 29262837
2018-03-31 10:55:00 Increased TCRgammadelta signal strength profoundly prohibited the development of all IL-17A-secreting gammadelta T cells, regardless of Vgamma usage, but promoted the development of gammadelta progenitors along the IFNgamma pathway. 28636936
2018-02-10 11:41:00 Findings indicate a role for memory gammadelta T cells in orchestrating protective immune responses against intestinal pathogens. 27402748
2017-12-02 11:12:00 Data show that inducible T cell co-stimulator (ICOS) deficient mice have a significant increase in the population of IL-17-producing Vgamma2+ gammadelta T cells in the thymus, spleen, lymph nodes and skin and exhibit exacerbated sensitization responses to 2,4-dinitrofluorobenzene. 27235509
2017-12-02 10:07:00 the majority of gammadelta T cells in the non-pregnant uterus, pregnant uterus, decidua and placenta of mice express the transcription factor RORgammat and produce interleukin-17 (IL-17). 27241697

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Type IDs
Synonymous Tcrdelta