| Type | Description |
|---|---|
| Definition | leukocyte immunoglobulin like receptor B4 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-12 13:09:00 | The observed inflammation was mainly due to BMDM-induced NF-kappaB signaling. In conclusion, our study demonstrates that LILRB4 deficiency plays a detrimental role in ALI-associated BMDM activation by prompting the NF-kappaB signal pathway. | 31138763 |
| 2019-10-12 10:29:00 | LILRB4 expression is decreased in hypertrophic hearts. | 30581005 |
| 2019-08-17 12:55:00 | Our data demonstrate that anti-LILRB4 CAR-T cells specifically target monocytic acute myeloid leukemia cells with no toxicity to normal hematopoietic progenitors. | 30131301 |
| 2019-04-06 10:09:00 | LILRB4 orchestrates tumour invasion pathways in monocytic leukaemia cells by creating an immunosuppressive microenvironment; LILRB4 represents a compelling target for the treatment of monocytic AML | 30333625 |
| 2018-11-10 11:59:00 | Results suggest that ILT3 played an important role in tumor progression in colorectal cancer by possible influence on CD45RO+ T cells in the tumor microenvironment. | 30126665 |
| Type | IDs |
|---|---|
| Synonymous | CD85K, ILT-3, ILT3, LIR-5, LIR5 |
| Gene |
UniProtKB-ID:
LIRB4_HUMAN,
A0A0A0MSZ8_HUMAN
UniprotKB:
Q8NHJ6,
A0A0A0MSZ8
UniParc:
UPI00034F2392,
UPI000013D889,
UPI00003B5D23,
UPI000066D982
EMBL:
BC026309,
AC009892,
AF283988,
CR609786,
CR542048,
AC011515,
AF025532,
AC245036,
AF189768,
U91925,
AC243962
Ensembl:
ENSG00000186818,
ENSG00000275730
KO:
hsa:11006
|
| Nucleutide sequences |
EMBL-CDS:
CAG46845.1,
AAB87666.1,
AAG02024.1,
AAH26309.1,
AAL36992.1,
AAB68665.1
Ensembl_TRS:
ENST00000391736,
ENST00000612454,
ENST00000614699,
ENST00000621693,
ENST00000430952
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000478542,
ENSP00000482234,
ENSP00000479829,
ENSP00000375616,
ENSP00000408995
RefSeq:
XP_016881706.1,
XP_024307099.1,
NP_001265359.2,
XP_016881705.1,
NP_001265356.2,
NP_001265357.2,
XP_016881704.1,
NP_001265355.2,
NP_001265358.2
|
| Others |
UniRef100:
UniRef100_A0A0A0MSZ8,
UniRef100_Q8NHJ6
UniRef90:
UniRef90_Q8NHJ6
UniRef50:
UniRef50_Q8NHJ6
UniGene:
Hs.67846,
Hs.731841
CCDS:
CCDS12902.1,
CCDS42618.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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