| Type | Description |
|---|---|
| Definition | glucuronidase, beta |
| Date | Results | Publications |
|---|---|---|
| 2017-11-26 00:38:00 | Administration of murine beta-glucuronidase to MPS VII mice at 4months of age, when bone disease was fully manifested, using lentiviral gene delivery resulted in a doubling of osteoclast numbers and a significant increase in attachment capacity (68% versus 29.4% in untreated MPS VII animals). Bone mineral volume rapidly decreased by 39% after gene therapy and fell within the normal range by 6months of age | 27692945 |
| 2015-11-28 10:31:00 | beta-Glucuronidase, a Regulator of Lyme Arthritis Severity, Modulates Lysosomal Trafficking and MMP-9 Secretion in Response to Inflammatory Stimuli | 26170381 |
| 2014-03-08 10:43:00 | GUSB modulates arthritis pathogenesis by preventing accumulation of proinflammatory glycosaminoglycans within inflamed joint tissue. | 24334460 |
| 2010-03-29 11:07:00 | The Gus plays a role in liver retinoid metabolism. | 19723663 |
| 2010-01-21 00:00:00 | data indicate the expression of beta-glucuronidase coordinated with testosterone level in male CBA mice but not C57BL/6 mice | 14556521 |
| Type | IDs |
|---|---|
| Synonymous | AI747421, Gur, Gus, Gus-r, Gus-s, Gus-t, Gus-u, Gut, asd, g |
| Gene |
UniProtKB-ID:
BGLR_MOUSE
UniprotKB:
P12265
UniParc:
UPI000002265A
EMBL:
BC071226,
M63836,
M28541,
M28540,
AK159526,
AK162436,
J03047,
AC161345,
CH466529,
AK136519,
AK150048,
J02836,
M19279
Ensembl:
ENSMUSG00000025534
KO:
mmu:110006
|
| Nucleutide sequences |
EMBL-CDS:
BAE36917.1,
AAA63309.1,
AAA37696.1,
AAA37697.1,
AAH71226.1,
BAE35155.1,
BAE23021.1,
BAE29265.1,
AAA98623.1,
AAA63308.1,
AAA63307.1,
EDL19485.1
Ensembl_TRS:
ENSMUST00000026613
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000026613
RefSeq:
XP_011239155.1,
NP_001343955.1,
NP_001343954.1,
NP_034498.1,
NP_001343956.1
|
| Others |
UniRef100:
UniRef100_P12265
UniRef90:
UniRef90_P12265
UniRef50:
UniRef50_P12265
UniGene:
Mm.3317
CCDS:
CCDS19705.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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