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10988 METAP2

10988

METAP2

methionyl aminopeptidase 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition methionyl aminopeptidase 2

研究结论

Date Results Publications
2019-02-09 11:24:00 Results show that methionine aminopeptidase-2 (MetAP2) regulates angiogenesis in glioblastoma and identify MetAP2-specific substrates that may serve as candidates for clinical assay development. 29116484
2018-04-21 11:24:00 MetAP1 and MetAP2 have roles in driving cell selectivity for a potent anti-cancer agent in synergy, by controlling glutathione redox state 27542228
2016-07-02 11:14:00 Suggest MetAP2 as important regulator of proliferation/apoptosis in non-small cell lung cancers. 26935506
2016-04-16 10:49:00 Nt-acetylation prevents the excision of the initiator methionine by MetAP2. 25886145
2014-11-08 11:12:00 Data indicate that methionine aminopeptidase 2 (MetAP2) contains a single disulfide bond that exists in oxidized and reduced states and influences enzyme function. 24700462

名称对应

Type IDs
Synonymous MAP2, MNPEP, p67eIF2
Gene
UniProtKB-ID: MAP2_HUMAN, A0A140VJE3_HUMAN, F8VQZ7_HUMAN
UniprotKB: P50579, A0A140VJE3, F8VQZ7
UniParc: UPI0000141182, UPI0000D4E0D4, UPI0000E00AB9, UPI000004493E
EMBL: AC018475, AK091730, AK300836, CH471054, HM005330, AK315559, BC013782, U13261, U29607
Ensembl: ENSG00000111142
KO: hsa:10988
Nucleutide sequences
EMBL-CDS: BAG62487.1, AAH13782.1, AAC63402.1, AAA82930.1, EAW97538.1, EAW97537.1, BAC03733.1, BAG37935.1, AEE60930.1
Ensembl_TRS: ENST00000323666, ENST00000261220, ENST00000546753, ENST00000551840
Protein sequencees
Ensembl_PRO: ENSP00000261220, ENSP00000325312, ENSP00000448169, ENSP00000450063
RefSeq: NP_001304111.1, NP_001317175.1, NP_006829.1, NP_001304112.1
Others
UniRef100: UniRef100_F8VQZ7, UniRef100_P50579
UniRef90: UniRef90_P50579, UniRef90_F8VQZ7
UniRef50: UniRef50_P50579
UniGene: Hs.444986
CCDS: CCDS9052.1, CCDS81723.1, CCDS81725.1

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