| Type | Description |
|---|---|
| Definition | coagulation factor XI |
| Date | Results | Publications |
|---|---|---|
| 2020-08-22 15:29:00 | A non-circulating pool of factor XI associated with glycosaminoglycans in mice. | 31125187 |
| 2019-02-02 12:05:00 | interfering with the FXIIa-FXI interaction could inhibit thromboinflammatory processes without compromising hemostasis. Inhibiting FXI activation with anti-FXI antibody 14E11 reduces myocardial ischemia-reperfusion injury. | 29365314 |
| 2018-07-21 11:18:00 | FXI(-/-) mice have a mild hemostatic defect after injury to the saphenous vein but not after transection of the tail or vessels in the abdominal wall. | 28677246 |
| 2018-05-05 11:50:00 | FXI protects against sepsis derived from Streptococcus pneumoniae or Klebsiella pneumoniae pneumonia at least in part by enhancing the phagocytic capacity of neutrophils by a mechanism that is independent of activation via FXIIa. | 28492700 |
| 2017-06-24 10:44:00 | FXI attenuates part of the allergic response to repeated administration of house dust mite in the airways by a mechanism that is independent of activation via FXII. | 27913422 |
| Type | IDs |
|---|---|
| Synonymous | 1600027G01Rik, AI503996, Cf11, FXI, PTA |
| Gene |
UniProtKB-ID:
FA11_MOUSE
UniprotKB:
Q91Y47
UniParc:
UPI0000023836
EMBL:
BC019485,
AK005546,
AF356627,
CH466554
Ensembl:
ENSMUSG00000031645
KO:
mmu:109821
|
| Nucleutide sequences |
EMBL-CDS:
EDL35542.1,
AAK40233.1,
AAH19485.1,
BAB24114.1
Ensembl_TRS:
ENSMUST00000034064
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000034064
RefSeq:
XP_006509308.1,
NP_082342.1,
XP_006509307.1,
XP_011240474.1
|
| Others |
UniRef100:
UniRef100_Q91Y47
UniRef90:
UniRef90_Q91Y47
UniRef50:
UniRef50_P03951
UniGene:
Mm.33326
CCDS:
CCDS22274.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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