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109801 Glo1

109801

Glo1

glyoxalase 1

protein-coding

Mus musculus

基因描述

Type Description
Definition glyoxalase 1

研究结论

Date Results Publications
2020-07-11 12:16:00 up-regulation of Glo1 in mice might be as another explanation for, at least some, effects attributed to before. 31526867
2020-06-20 12:37:00 The protein expression of GLO1 in basilar arteries from hypertensive mice was decreased, and GLO1 expression was negatively correlated with medial cross-sectional area and blood pressure in basilar arteries during hypertension. 31420161
2019-12-28 11:47:00 Data suggest that GLO1 rescues bone marrow-derived progenitor cell dysfunction and facilitates wound healing in diabetic animals, at least partly through preventing methylglyoxal-induced impairment of IRE1alpha expression and activity. 30885990
2019-07-06 10:41:00 The objective of the present study was to detect whether overexpression of methylglyoxal-metabolizing enzyme glyoxalase-1 (GLO1), which reduces reactive oxygen species in Diabetic Adipose-Derived Stem Cells, can restore their proangiogenic function in a streptozotocin-induced diabetic mice model of critical limb ischemia. 28170200
2018-02-03 10:43:00 Transgenic mice overexpressing Glo1 on both FVB/NJ (FVB) or C57BL/6J (B6) backgrounds showed increased voluntary EtOH consumption compared to their wild-type littermates. Transgenic Glo1 knockdown mice on a B6 background showed decreased voluntary EtOH consumption. Genetic manipulations of Glo1 had no effect on sucrose, saccharin or water consumption. 26691867

名称对应

Type IDs
Synonymous 0610009E22Rik, 1110008E19Rik, 2510049H23Rik, AW550643, GLY1, Glo-1, Glo-1r, Glo-1s, Glo1-r, Glo1-s, Qglo
Gene
UniProtKB-ID: LGUL_MOUSE, A5GZX3_MOUSE
UniprotKB: Q9CPU0, A5GZX3
UniParc: UPI0000003FBA
EMBL: AK003567, AK005055, AK049703, BC024663, BC081432, AK031832, DQ487162, AK002386, DQ487161
Ensembl: ENSMUSG00000024026
KO: mmu:109801
Nucleutide sequences
EMBL-CDS: BAB23781.1, AAH24663.1, AAH81432.1, BAC33882.1, BAC27570.1, BAB22863.1, BAB22060.1, ABF48484.1, ABF48483.1
Ensembl_TRS: ENSMUST00000235547, ENSMUST00000236335, ENSMUST00000167624
Protein sequencees
Ensembl_PRO: ENSMUSP00000126586, ENSMUSP00000157858, ENSMUSP00000158296
RefSeq: NP_001107032.1, NP_079650.3
Others
UniRef100: UniRef100_Q9CPU0
UniRef90: UniRef90_Q9CPU0
UniRef50: UniRef50_Q04760
UniGene: Mm.261984
CCDS: CCDS28600.1

全选

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研究热度

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