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10979 FERMT2

10979

FERMT2

fermitin family member 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition fermitin family member 2

研究结论

Date Results Publications
2021-03-13 13:18:00 Kindlin2 suppresses cervical cancer cell migration through AKT/mTORmediated autophagy induction. 32377753
2020-12-26 13:13:00 The focal adhesion protein kindlin-2 controls mitotic spindle assembly by inhibiting histone deacetylase 6 and maintaining alpha-tubulin acetylation. 32169902
2020-09-05 13:54:00 Elevated kindlin-2 promotes tumour progression and angiogenesis through the mTOR/VEGFA pathway in melanoma. 31427543
2020-05-16 12:53:00 miR-338-5p expression is lower in esophageal squamous cell carcinoma (ESCC) cells compared with normal cells. miR-338-5p reduced cell proliferation, colony formation, migration and cisplatin resistance in an ESCC cell line, CE-81T. Luciferase assays showed the direct binding between miR-338-5p and the 3' untranslated region of FERMT2 suggesting that miR-338-5p may play an antioncogenic role in ESCC via repressing FERMT2. 30576425
2019-10-19 12:22:00 Results found that high FERMT2 expression correlated with poor disease-free survival of melanoma patients. The stability of its mRNA is regulated by the complex p62-IGF2BP1. 30581152

名称对应

Type IDs
Synonymous KIND2, MIG2, PLEKHC1, UNC112, UNC112B, mig-2
Gene
UniProtKB-ID: FERM2_HUMAN, A0A024R687_HUMAN
UniprotKB: Q96AC1, A0A024R687
UniParc: UPI00015DFD70, UPI000000CC30, UPI0000073CC9
EMBL: BX161467, CH471061, BC011125, Z24725, BC017327, AF443279, AL352979, AL139317, EU979385
Ensembl: ENSG00000073712
KO: hsa:10979
Nucleutide sequences
EMBL-CDS: ACH73257.1, AAN75823.1, CAA80852.1, AAH17327.1, CAD61925.1, EAW80620.1, EAW80619.1
Gene_ORFName: hCG_20966
Ensembl_TRS: ENST00000395631, ENST00000553373, ENST00000399304, ENST00000343279, ENST00000341590
Protein sequencees
Ensembl_PRO: ENSP00000382243, ENSP00000451084, ENSP00000378993, ENSP00000340391, ENSP00000342858
RefSeq: NP_001128471.1, XP_006720073.1, XP_006720072.1, XP_005267342.1, NP_001128472.1, NP_006823.1, XP_006720071.1
Others
UniRef100: UniRef100_Q96AC1
UniRef90: UniRef90_Q96AC1
UniRef50: UniRef50_Q96AC1
UniGene: Hs.509343
CCDS: CCDS45107.1, CCDS9713.1, CCDS45108.1

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