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10973 ASCC3

10973

ASCC3

activating signal cointegrator 1 complex subunit 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition activating signal cointegrator 1 complex subunit 3

研究结论

Date Results Publications
2020-11-21 13:23:00 The interaction of DNA repair factors ASCC2 and ASCC3 is affected by somatic cancer mutations. 33139697
2017-06-03 10:58:00 UV exposure results in spatial restriction of transcription and slower elongation, with the result that only the promoter-proximal 20-25 kb are efficiently transcribed; these events underlie a switch to expression of short mRNA isoforms and preferential use of alternative last exons in a number of genes, including ASCC3. 28215706
2016-06-28 10:47:00 ASCC3 Gene Polymorphism was associated with Chronic Hepatitis B. 26536629
2013-11-30 10:47:00 Silencing of ASCC3 resulted in upregulation of multiple antiviral interferon-stimulated genes, which correlated with inhibition of infection of several positive-strand RNA viruses. 23781071
2011-12-31 10:39:00 DNA unwinding by ASCC3 helicase is coupled to ALKBH3-dependent DNA alkylation repair and cancer cell proliferation. 22055184

名称对应

Type IDs
Synonymous ASC1p200, HELIC1, RNAH
Gene
UniProtKB-ID: ASCC3_HUMAN, B4DR60_HUMAN
UniprotKB: Q8N3C0, B4DR60
UniParc: UPI000006FDAA, UPI00017A7AA7, UPI000014145A, UPI0001E8F63A
EMBL: Z86062, CH471051, BC050681, AJ223948, AK299117, AL356122, BC125212, BC026066, AK315197, AL834463, AL133338, AL591585, BC125211, AY013288, AL121965
Ensembl: ENSG00000112249
KO: hsa:10973
Nucleutide sequences
EMBL-CDS: AAH50681.1, BAG37637.1, AAI25212.1, AAH26066.1, CAA11679.1, EAW48449.1, AAG45474.1, CAD39122.1, AAI25213.1, BAG61172.1
Ensembl_TRS: ENST00000522650, ENST00000369162, ENST00000369143
Protein sequencees
Ensembl_PRO: ENSP00000358139, ENSP00000358159, ENSP00000430769
RefSeq: NP_006819.2, NP_071374.1, XP_011533698.1, XP_011533697.1, XP_016865695.1, XP_016865694.1, XP_011533696.1, XP_024302084.1, NP_001271200.1
Others
UniRef100: UniRef100_Q8N3C0, UniRef100_B4DR60
UniRef90: UniRef90_B4DR60, UniRef90_Q8N3C0
UniRef50: UniRef50_Q8N3C0, UniRef50_A0A314YIE2
UniGene: Hs.486031
CCDS: CCDS5047.1, CCDS5046.1, CCDS75497.1

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