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10970 CKAP4

10970

CKAP4

cytoskeleton associated protein 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition cytoskeleton associated protein 4

研究结论

Date Results Publications
2021-03-20 13:31:00 The RBP1-CKAP4 axis activates oncogenic autophagy and promotes cancer progression in oral squamous cell carcinoma. 32587255
2020-09-26 13:05:00 p63 overexpression in the epidermis of spiny keratoderma. 31696529
2020-08-22 15:27:00 Dynamic palmitoylation controls the microdomain localization of the DKK1 receptors CKAP4 and LRP6. 31744930
2020-05-30 11:16:00 CKAP4 was secreted with small extracellular vesicles (SEVs) from pancreatic ductal adenocarcinoma (PDAC) cells, and the SEVs exhibited the characteristics of exosomes. The secretion of CKAP4-containing exosomes was mediated by DKK1-dependent endocytosis routes and required exosome biogenesis molecules. The serum CKAP4 levels were higher in patients with PDAC than healthy control individuals. 30610103
2020-02-29 11:29:00 High-speed (40 ms/frame) live cell STED imaging shows that RTN4a and CLIMP-63 regulate dynamic nanoscale lumenal compartmentalization along peripheral ER tubules. RTN4a enhances and CLIMP-63 disrupts the local accumulation of lumenal ERmoxGFP at spatially defined sites along ER tubules. 31469817

名称对应

Type IDs
Synonymous CLIMP-63, ERGIC-63, p63
Gene
UniProtKB-ID: CKAP4_HUMAN, A0A024RBH2_HUMAN
UniprotKB: Q07065, A0A024RBH2
UniParc: UPI00000723B9
EMBL: BC082972, AK223563, CH471054, AC079174, BC094824, X69910
Ensembl: ENSG00000136026
KO: hsa:10970
Nucleutide sequences
EMBL-CDS: CAA49535.2, AAH94824.1, BAD97283.1, AAH82972.1, EAW97773.1, EAW97772.1
Gene_ORFName: hCG_16102
Ensembl_TRS: ENST00000378026
Protein sequencees
Ensembl_PRO: ENSP00000367265
RefSeq: NP_006816.2
Others
UniRef100: UniRef100_Q07065
UniRef90: UniRef90_Q07065
UniRef50: UniRef50_Q07065
UniGene: Hs.74368
CCDS: CCDS9103.1

全选

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研究热度

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