| Type | Description |
|---|---|
| Definition | arrestin, beta 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:59:00 | Biological Role of Arrestin-1 Oligomerization. | 32948676 |
| 2020-06-27 10:07:00 | Barr1 can directly interact with Epac2; sulfonylureas such as glibenclamide promote Barr1/Epac2 complex formation, triggering enhanced Rap1 signaling and insulin secretion | 31184597 |
| 2020-06-06 13:33:00 | betaarr1 plays a role in radiation-induced intestinal injury. Intestinal betaarr1 was highly expressed in radiation enteritis and in a radiation model. betaarr1 knockout (KO) or knockdown mice exhibited increased proliferation in intestinal Lgr5+ stem cell, crypt reproduction, and survival following radiation. betaarr1 knockdown with siRNA enhanced intestinal Lgr5(+) stem cell proliferation after radiation via targetin... | 31207192 |
| 2020-03-14 10:57:00 | results for the first time demonstrate that melatonin safeguards against nonalcoholic fatty liver disease by eliminating ASK1 activation via inhibiting TRAFs-mediated ASK1 deubiquitination and stabilization in a beta-arrestin-1 dependent manner. | 31541591 |
| 2020-02-15 11:52:00 | Using skeletal muscle (SKM)-specific knockout (KO) mouse lines, study showed that the loss of SKM Barr2, but not of SKM Barr1, resulted in mild improvements in glucose tolerance in diet-induced obese mice. Data indicate that SKM beta-arrestins play only rather subtle roles (SKM Barr2) in regulating whole-body glucose homeostasis and SKM insulin sensitivity. | 31622341 |
| Type | IDs |
|---|---|
| Synonymous | 1200006I17Rik, AW208571, G430100A01Rik |
| Gene |
UniProtKB-ID:
ARRB1_MOUSE
UniprotKB:
Q8BWG8
UniParc:
UPI00000EAB68,
UPI00000EA7C7
EMBL:
AK165514,
AK147508,
BC108969,
AK052588,
BC108970,
AK144054,
AK090090
Ensembl:
ENSMUSG00000018909
KO:
mmu:109689
|
| Nucleutide sequences |
EMBL-CDS:
BAC35050.1,
BAE27962.1,
AAI08971.1,
BAE25673.1,
BAE38230.1,
AAI08970.1,
BAC41087.1
Ensembl_TRS:
ENSMUST00000032995,
ENSMUST00000098266
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000032995,
ENSMUSP00000095866
RefSeq:
NP_796205.1,
XP_011239946.1,
XP_006507262.1,
XP_006507263.1,
NP_835738.1,
XP_006507261.1,
XP_036008462.1
|
| Others |
UniRef100:
UniRef100_Q8BWG8
UniRef90:
UniRef90_P29066
UniRef50:
UniRef50_P29066
UniGene:
Mm.260193
CCDS:
CCDS40032.1,
CCDS21484.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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