Hyal3 - hyaluronoglucosaminidase 3-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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109685 Hyal3

基因描述

Type	Description
Definition	hyaluronoglucosaminidase 3

研究结论

Date	Results	Publications
2012-04-07 10:56:00	Data show that Hyal-1, but not Hyal-3,is an ovarian regulator factor for follicle development, and show an interrelationship between this enzyme and the follistatin/activin/Smad3 pathway.	21732362
2011-01-01 10:54:00	Hyal3 null sperm showed delayed cumulus penetration and reduced acrosomal exocytosis.	20586096
2010-01-21 00:00:00	HYAL3 does not play a major role in constitutive hyaluronan degradation	18762256
2010-01-21 00:00:00	Characterization of the murine hyaluronidase gene region reveals complex organization and cotranscription of Hyal1 with downstream genes, Fus2 and Hyal3.	11929860
2010-01-21 00:00:00	Hyal3 may contribute to hyaluronan metabolism by augmenting the activity of Hyal1.	18234732

名称对应

Type	IDs
Synonymous	Hyl3
Gene	UniProtKB-ID: HYAL3_MOUSE UniprotKB: Q8VEI3 UniParc: UPI0000024CEC EMBL: BC018457, AF075576, AY048681, AF074489, AF338323, AL672219 Ensembl: ENSMUSG00000036091 KO: mmu:109685
Nucleutide sequences	EMBL-CDS: AAL54883.1, AAH18457.1, AAL06145.1, AAL54882.1, AAL57175.1 Ensembl_TRS: ENSMUST00000148440, ENSMUST00000040059
Protein sequencees	Ensembl_PRO: ENSMUSP00000042667, ENSMUSP00000119499 RefSeq: NP_821139.2
Others	UniRef100: UniRef100_Q8VEI3 UniRef90: UniRef90_Q8VEI3 UniRef50: UniRef50_Q8VEI3 UniGene: Mm.447916 CCDS: CCDS23499.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
21732362	Hyal-1 but not Hyal-3 deficiency has an impact on ovarian folliculogenesis and female fertility by altering the follistatin/activin/Smad3 pathway and the apoptotic process. J. Cell. Physiol. Karine Dumaresq-Doiron , Lydia Edjekouane , Adriana Mari Orimoto , Paule HÃ©lÃ©na Yoffou , Lara Gushulak , Barbara Triggs-Raine , Euridice Carmona	2012-05-01	Hyal3, Hyal1
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21677750	A conditional knockout resource for the genome-wide study of mouse gene function. Nature William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley	2011-06-15	-
20586096	Acidic hyaluronidase activity is present in mouse sperm and is reduced in the absence of SPAM1: evidence for a role for hyaluronidase 3 in mouse and human sperm. Mol Reprod Dev Kristen L Reese , Rolands G Aravindan , Genevieve S Griffiths , Minghai Shao , Yipei Wang , Deni S Galileo , Vasantha Atmuri , Barbara L Triggs-Raine , Patricia A Martin-Deleon	2010-09-01	-
18772348	Skeletal and hematological anomalies in HYAL2-deficient mice: a second type of mucopolysaccharidosis IX? FASEB J. Laurence Jadin , Xiaoli Wu , Hao Ding , Gregory I Frost , CÃ©cile Onclinx , Barbara Triggs-Raine , Bruno Flamion	2008-12-01	Hyal3, Hyal1, Hyal2, Ifrd2, Rassf1, Nat6, Tusc2
18653706	Mammalian hyaluronidase induces ovarian granulosa cell apoptosis and is involved in follicular atresia. Endocrinology Adriana M Orimoto , Karine Dumaresq-Doiron , Jin-Yi Jiang , Nongnuj Tanphaichitr , Benjamin K Tsang , Euridice Carmona	2008-11-01	Hyal3, Hyal1, Hyal2
18762256	Hyaluronidase 3 (HYAL3) knockout mice do not display evidence of hyaluronan accumulation. Matrix Biol. Vasantha Atmuri , Dianna C Martin , Richard Hemming , Alex Gutsol , Sharon Byers , Solmaz Sahebjam , James A Thliveris , John S Mort , Euridice Carmona , Judy E Anderson , Shyamala Dakshinamurti , Barbara Triggs-Raine	2008-10-01	Hyal3
18234732	Mouse Hyal3 encodes a 45- to 56-kDa glycoprotein whose overexpression increases hyaluronidase 1 activity in cultured cells. Glycobiology Richard Hemming , Dianna C Martin , Elzbieta Slominski , James I Nagy , Andrew J Halayko , Steven Pind , Barbara Triggs-Raine	2008-04-01	Hyal3
18267097	Endocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesis. Dev Cell Kryn Stankunas , Calvin T Hang , Zhi-Yang Tsun , Hanying Chen , Nathan V Lee , Jiang I Wu , Ching Shang , J Henri Bayle , Weinian Shou , M Luisa Iruela-Arispe , Ching-Pin Chang	2008-02-01	-
15489334	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team	2004-10-01	Ldlrap1, Dnajc3, Rnaset2a, Btnl1, Isg15, Cyp3a41b, Ly6c2, Ccl21b, Eif3j2, Mup18, Lrrc19, Rcc1, 1700047I17Rik2, Pcsk9, Adat3, Tdrd7, Sco2, Gpr153, Pafah2, Gm44504, H6pd, Adprhl2, Gpn2, Rusc2, Stx12, Ppp1r8, Smpdl3b, Fam46b, Bsdc1, Slc44a1, Zfand2a, Rubcn, Kifc1, Pifo, C030017K20Rik, Cbarp, Rpl5, Micalcl, Atg14, Lrrc8c, Noc4l, Nsun5, Psph, Trrap, Mapre3, Ube3c, Tbc1d14, Hscb, Tyw1, Emilin1, Rab28, Pot1a, Parp11, Tada3, Tra2a, Brk1, Fbxl14, Phrf1, Plekha1, Gm21975, Ric8a, Mob2, Prkd2, Ccp110, Vrk3, Grwd1, Nlrp6, Trim68, Psip1, Spred3, Faap24, Ints4, Rrp8, Unc45a, Igflr1, Sf3b3, D8Ertd738e, Usb1, Champ1, Smim19, Exoc8, Gadd45gip1, Phkb, Dohh, Fam192a, Enkd1, Taf5l, Zdhhc7, Snapc2, Ak6, Gpat4, Dcun1d2, Ankrd10, Cog4, Hinfp, Lars2, Xylb, Imp3, Cmtm7

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