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109620 Dsp

109620

Dsp

desmoplakin

protein-coding

Mus musculus

基因描述

Type Description
Definition desmoplakin

研究结论

Date Results Publications
2019-11-30 12:15:00 Study indicates that an improperly folded desmoplakin (DSP) plakin repeat domain 2/B diminishes the interaction of DSP with epidermal keratins and desmin that probably leads to cutaneous and cardiac defects, respectively. 29878302
2017-12-23 10:33:00 Deletion of Dsp under the transcriptional regulation of the CSPG4 locus led to phenotype resembling the human cardiocutaneous syndromes. 29018034
2017-04-29 10:12:00 Conditional heterozygous deletion of Dsp in mice led to increased fibroadipogenesis in the heart and mild cardiac dysfunction. 27121621
2016-05-21 10:21:00 Our data suggest that endurance exercise accelerates arrhythmogenic ventricular cardiomyopathy pathogenesis in transgenic DSP mice 26545710
2015-05-02 10:05:00 GSK3- and PRMT-1-dependent modifications of desmoplakin control desmoplakin-cytoskeleton dynamics. 25733715

名称对应

Type IDs
Synonymous 2300002E22Rik, 5730453H04Rik, AA407887, AA407888, AW109828, DP, rul
Gene
UniProtKB-ID: DESP_MOUSE, E9PZW0_MOUSE
UniprotKB: E9Q557, E9PZW0
UniParc: UPI0000606D33, UPI0000429352
EMBL: AC140331
Ensembl: ENSMUSG00000054889
KO: mmu:109620
Nucleutide sequences
Ensembl_TRS: ENSMUST00000124830, ENSMUST00000127906
Protein sequencees
Ensembl_PRO: ENSMUSP00000115062, ENSMUSP00000117252
RefSeq: NP_076331.2, XP_006516595.1
Others
UniRef100: UniRef100_E9PZW0, UniRef100_E9Q557
UniRef90: UniRef90_P15924, UniRef90_M3XNC1
UniRef50: UniRef50_P15924, UniRef50_P15924-2
UniGene: Mm.355327
CCDS: CCDS49239.1

全选

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研究热度

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