| Type | Description |
|---|---|
| Definition | sorcin |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 10:55:00 | Presence of Pb(2+) ions within the hepatocytes reduces transcript and protein levels of sorcin, a cytosolic adaptor partner of ChREBP. Adenovirus-mediated overexpression of sorcin in Pb(2+) exposed hepatocytes and an in vivo mouse model ameliorates liver steatosis and hepatotoxicity. These results present evidence that sorcin is an essential regulator of Pb2+-induced dyslipidemia in the liver. | 31309533 |
| 2019-09-14 11:41:00 | Sorcin is involved in the regulation of Ca(+2)-mediated angiogenesis via VEGF/PI3K/Akt pathway in endometrial cells. | 29273681 |
| 2019-06-29 11:52:00 | sorcin deficiency may trigger cardiac ventricular arrhythmias due to Ca(2+) disturbances | 29174767 |
| 2017-06-10 11:04:00 | Sorcin links pancreatic beta cells lipotoxicity to calcium stores and provides a target for intervention in type 2 diabetes. | 26822088 |
| 2012-08-11 11:27:00 | Regulation of calcium signaling and cardiac contractility by miR-1 regulated sorcin expression plays a fundamental role in the maintenance of normal cardiac function and in the pathogenesis of cardiac dysfunction. | 22326846 |
| Type | IDs |
|---|---|
| Synonymous | 2210417O06Rik, 2900070H08Rik, Sor |
| Gene |
UniProtKB-ID:
SORCN_MOUSE
UniprotKB:
Q6P069
UniParc:
UPI00000E6158,
UPI0000237E3B
EMBL:
AK146071,
AK008970,
BC065790,
AK134747,
AK168900,
AK008783,
AK008404,
AK168572,
AK146911,
AK168792
Ensembl:
ENSMUSG00000003161
KO:
mmu:109552
|
| Nucleutide sequences |
EMBL-CDS:
BAE40442.1,
BAE26876.1,
BAB25891.1,
BAB25997.1,
AAH65790.1,
BAB25652.1,
BAE40625.1,
BAE40716.1,
BAE22266.1,
BAE27523.1
Ensembl_TRS:
ENSMUST00000088786,
ENSMUST00000148633
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000118221,
ENSMUSP00000086165
RefSeq:
XP_006503590.1,
NP_001074443.1,
XP_017176089.1,
NP_079894.2
|
| Others |
UniRef100:
UniRef100_Q6P069
UniRef90:
UniRef90_Q6P069
UniRef50:
UniRef50_Q6P069
UniGene:
Mm.96211
CCDS:
CCDS19079.1,
CCDS39009.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员