| Type | Description |
|---|---|
| Definition | Sec61 translocon beta subunit |
| Date | Results | Publications |
|---|---|---|
| 2019-06-08 10:48:00 | Sec61beta may stabilize protein translocation by linking translocon complex to microtubule and provide insight into the physiological function of ER-microtubule interaction | 29168059 |
| 2017-09-16 10:34:00 | used whole exome sequencing in a discovery cohort of 102 unrelated patients who were excluded for mutations in the 2 most common polycystic liver disease genes, PRKCSH and SEC63, to identify heterozygous loss-of-function mutations in 3 additional genes, ALG8, GANAB, and SEC61B. Similarly to PRKCSH and SEC63, these genes encode proteins that are integral to the protein biogenesis pathway in the endoplasmic reticulum. | 28375157 |
| 2015-06-20 13:13:00 | These data confirm that the exocyst is preferentially involved in basolateral protein translation and translocation, and may well act through the phosphorylation of Sec61beta. | 23037926 |
| 2015-01-24 11:01:00 | Sec61beta overexpression increased tight junction modulation rates, in conjunction with enhanced delivery of claudin-4 from and to plasma membranes. | 24882410 |
| 2013-01-26 10:49:00 | Sec61beta-KD cells also exhibited altered ATP7A cellular distribution. | 22710939 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
SC61B_HUMAN
UniprotKB:
P60468
UniParc:
UPI000000096E
EMBL:
BC001734,
AL137067,
L25085,
CR456883
Ensembl:
ENSG00000106803
KO:
hsa:10952
|
| Nucleutide sequences |
EMBL-CDS:
CAG33164.1,
AAH01734.1,
AAA19706.1
Ensembl_TRS:
ENST00000223641
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000223641
RefSeq:
NP_006799.1
|
| Others |
UniRef100:
UniRef100_P60468
UniRef90:
UniRef90_P60468
UniRef50:
UniRef50_P60468
UniGene:
Hs.191887
CCDS:
CCDS6741.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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