| Type | Description |
|---|---|
| Definition | serine protease 21 |
| Date | Results | Publications |
|---|---|---|
| 2015-05-09 11:44:00 | Testisin activates PAR-2, inducing PAR-2 loss from the cell surface, internalization, and cellular signaling. | 25519908 |
| 2010-05-03 12:09:00 | Testisin may promote carcinogenesis by inhibiting tumor suppressor activity of maspin. | 20211623 |
| 2010-01-21 00:00:00 | Loss of Testisin is caused, at least in part, by DNA hypermethylation and histone deacetylation, and suggest a tumour suppressor role for Testisin in testicular tumorigenesis. | 15685234 |
| 2010-01-21 00:00:00 | The results demonstrate for the first time that aberrant methylation of specific CpG sites near the transcription initiation site is an important factor in testisin gene silencing in TGCT. | 16810501 |
| 2010-01-21 00:00:00 | These data suggest that aberrant regulation of PRSS21 may underlie certain secondary male infertility syndromes, such as "easily decapitated" spermatozoa in humans. | 19571264 |
| Type | IDs |
|---|---|
| Synonymous | ESP-1, ESP1, TEST1, TESTISIN |
| Gene |
UniProtKB-ID:
TEST_HUMAN
UniprotKB:
Q9Y6M0
UniParc:
UPI000004813E,
UPI000002B520,
UPI000002B51F
EMBL:
AB031330,
AB031329,
AF058301,
BC074999,
AB031331,
AY359034,
BC075000,
AF058300
Ensembl:
ENSG00000282838,
ENSG00000007038
KO:
hsa:10942
|
| Nucleutide sequences |
EMBL-CDS:
AAH74999.1,
AAD41588.1,
BAA83520.1,
AAF79020.1,
BAA83521.1,
AAF79019.1,
AAH75000.1,
AAQ89393.1,
BAA89532.1
Gene_ORFName:
UNQ266/PRO303
Ensembl_TRS:
ENST00000634351,
ENST00000634454,
ENST00000005995,
ENST00000450020
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000005995,
ENSP00000489081,
ENSP00000489315,
ENSP00000407741
RefSeq:
XP_016878365.1,
XP_016878367.1,
XP_016878364.1,
NP_659205.1,
NP_001257381.1,
NP_006790.1,
NP_659206.1,
XP_016878366.1
|
| Others |
UniRef100:
UniRef100_Q9Y6M0
UniRef90:
UniRef90_Q9Y6M0
UniRef50:
UniRef50_Q9Y6M0
UniGene:
Hs.72026
CCDS:
CCDS10478.1,
CCDS45388.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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