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10936 GPR75

10936

GPR75

G protein-coupled receptor 75

protein-coding

Homo sapiens

基因描述

Type Description
Definition G protein-coupled receptor 75

研究结论

Date Results Publications
2020-05-16 10:48:00 Study results show for the first time the involvement of the 20-HETE-GPR75 receptor in the activation of intracellular signaling known to be stimulated in cell malignant transformations leading to the differentiation of PC-3 prostate cancer cells towards a more aggressive phenotype. GPR75 receptor stimulation is necessary for the pro-metastatic actions of 20-HETE in androgen insensitive prostate cancer cells. 31760076
2019-06-29 12:30:00 This study explored the interaction of CCL5 with GPR75, an orphan receptor of the Gqalpha family of GPCRs, which appears to be expressed more abundantly in neuron-like cells than astrocytes. 29772059

名称对应

Type IDs
Synonymous GPRchr2, WI31133
Gene
UniProtKB-ID: GPR75_HUMAN
UniprotKB: O95800
UniParc: UPI0000050454
EMBL: AC008068, BC067475, CH471053, BC067476, AF101472, AF072693, AK314885
Ensembl: ENSG00000119737
KO: hsa:10936
Nucleutide sequences
EMBL-CDS: AAY15018.1, BAG37399.1, AAH67475.1, AAD19849.1, AAD22770.1, EAX00162.1, AAH67476.1
Ensembl_TRS: ENST00000394705
Protein sequencees
Ensembl_PRO: ENSP00000378195
RefSeq: NP_006785.1
Others
UniRef100: UniRef100_O95800
UniRef90: UniRef90_O95800
UniRef50: UniRef50_Q6X632
UniGene: Hs.40763
CCDS: CCDS1849.1

全选

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研究热度

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