Type | Description |
---|---|
Definition | peroxiredoxin 3 |
Date | Results | Publications |
---|---|---|
2020-07-11 12:09:00 | High immunohistochemical expression of PRDX3 in primary uveal melanoma (UM) tissue is associated with metastasis and poor survival. | 31771972 |
2020-05-09 12:12:00 | the results show that PPPCD is associated with an alteration of corneal biomechanics and a novel missense variant in PRDX3. | 31782998 |
2020-02-08 10:52:00 | Here generated are a range of peroxiredoxin 3 mutants with either a decreased or knocked out ability to stack, and used both imaging and solution studies to show that peroxiredoxin 3 stacks through electrostatic interactions that are stabilised by a hydrogen bonding network. | 30885432 |
2020-02-01 11:45:00 | Upregulated expression of Prdx3 and Prdx5 has been reported in different cancer types involving their association with different factors, such as transcription factors, micro RNAs, tumor suppressors, response elements, and oncogenic genes. Also, increased production of Prdx3 and Prdx5 is associated with the development of chemoresistance in certain types of cancers and it leads to further complications. [review] | 31500275 |
2019-12-14 12:23:00 | human Prx3 rapidly reduces peroxynitrite; Prx3 intrinsic fluorescence presents biphasic changes upon oxidation;Peroxynitrite in excess leads to Prx3 nitration and hyperoxidation;Both Prx3 and Prx5 are predicted to be main targets for mitochondrial peroxynitrite. | 30391677 |
Type | IDs |
---|---|
Synonymous | AOP-1, AOP1, HBC189, MER5, PRO1748, SP-22, prx-III |
Gene |
UniProtKB-ID:
PRDX3_HUMAN,
A0A384MTR2_HUMAN
UniprotKB:
P30048,
A0A384MTR2
UniParc:
UPI00001B216B,
UPI0000000C81
EMBL:
BC007062,
BC022373,
GQ891458,
D49396,
BC111397,
CH471066,
BC059169,
BC008435,
DQ298752,
CR450344,
BC002685,
AK313169,
AL355861,
BC009601,
BT020007,
BC021691
Ensembl:
ENSG00000165672
KO:
hsa:10935
|
Nucleutide sequences |
EMBL-CDS:
AAH08435.1,
AAV38810.1,
CAG29340.1,
AAH22373.1,
AAH07062.1,
AAI11398.1,
AAH21691.1,
BAA08389.1,
AAH09601.1,
AAH59169.1,
EAW49399.1,
BAG35987.1,
ABB84468.1,
AAH02685.1,
ADO22320.1,
EAW49397.1
Gene_ORFName:
hCG_37898
Ensembl_TRS:
ENST00000298510
|
Protein sequencees |
Ensembl_PRO:
ENSP00000298510
RefSeq:
NP_001289201.1,
NP_006784.1
|
Others |
UniRef100:
UniRef100_P30048
UniRef90:
UniRef90_P30048
UniRef50:
UniRef50_P30048
UniGene:
Hs.523302
CCDS:
CCDS7611.1
|
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Refseq |
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